Senior Research Associate I, Analytical Chemistry

Associate Director, Clinical Quality Assurance

Senior Manager, Biostatistics

Translational Sciences Biomarker Specialist

Senior Manager, Regulatory Affairs 

Director, Medical Writer

Principal Biostatistician, Biostatistics

Senior Clinical Site Liaison

Clinical Site Liaison, I

1910 Genetics

20n Bio

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4D Molecular Therapeutics

64x Bio

8Biomed

A-Alpha Bio

A2 Biotherapeutics

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AB Studio

Abalone Bio

Abata Therapeutics

Abeona Therapeutics

Abintus Bio

Abiosciences

Absci

Accelevir Diagnostics

Accent Therapeutics

ACELYRIN

Acepodia

Achieve Life Sciences

Acrivon Therapeutics

Acutis Diagnostics

Adaptive Phage Therapeutics

Adcentrx Therapeutics

Adicet Bio

Aditum Bio

adMare BioInnovations

Admera Health

Adverum Biotechnologies

adyn

Aeglea BioTherapeutics

Aether Bio

Affini-T Therapeutics

Affinia Therapeutics

Affinivax

AgBiome

Agena Bioscience

Akero Therapeutics

Akouos

Alamar Biosciences

Alector

AlivaMab Discovery Services

Alkahest

Alladapt Immunotherapeutics

Allakos

Allarta Life Science

Allay Therapeutics

AlloVir

Alloy Therapeutics

AllStripes

Alltrna

Alpine Immune Sciences

Altis Biosystems

Alto Neuroscience

AltPep

Alumis

Alveo Technologies

ALX Oncology

Alzheon

Ambagon Therapeutics

Amberstone Biosciences

Ambys Medicines

Amylyx

AN2 Therapeutics

Andes

Angiocrine Bioscience

AnHeart Therapeutics

Annexon Biosciences

Ansa Biotechnologies

Antheia

Apollomics

Appia Bio

Applied Molecular Transport

Apriori Bio (Flagship)

Aptevo Therapeutics

Apton Biosystems

Aptose Biosciences

Aquinnah Pharmaceuticals

Arbor Biotechnologies

Arcadia Science

Arcellx

Arcturus Therapeutics

Arcutis Biotherapeutics

Arima Genomics

Ark Biotech

Arkuda Therapeutics

Armata Pharmaceuticals

Aro Biotherapeutics

Arpeggio Biosciences

Arrakis Therapeutics

Arranta Bio

ArsenalBio

Artisan Bio

Artiva Biotherapeutics

Ascidian Therapeutics

Ascribe Bioscience

Asher Biotherapeutics

Asimov

Pliant Therapeutics is understanding the molecular drivers of fibrotic diseases to identify safer and more effective therapies for patients. Fibrosis occurs when cells repair tissue damage through the formation of fibrotic scars, which when overactivated can cause irreparable damage and disease. TGF-β is a key driver of fibrosis that investigational therapies are targeting; however, it risks toxicity to a patient’s healthy tissues. Instead, Pliant is using their expertise in integrin biology, proteins downstream of TGF-β in the fibrosis cascade, to identify more selective therapies. Pliant is building a pipeline of integrin inhibitors using their screening platform, live fibrotic human tissue assays and biomarker assays. Their lead candidate, PLN-74809, is in clinical trials.  

<p>Pliant Therapeutics is understanding the molecular drivers of fibrotic diseases to identify safer and more effective therapies for patients. Fibrosis occurs when cells repair tissue damage through the formation of fibrotic scars, which when overactivated can cause irreparable damage and disease. TGF-β is a key driver of fibrosis that investigational therapies are targeting; however, it risks toxicity to a patient’s healthy tissues. Instead, Pliant is using their expertise in integrin biology, proteins downstream of TGF-β in the fibrosis cascade, to identify more selective therapies. Pliant is building a pipeline of integrin inhibitors using their screening platform, live fibrotic human tissue assays and biomarker assays. Their lead candidate, PLN-74809, is in clinical trials.  </p>


Pliant Therapeutics

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