WaVe Life Sciences

WaVe Life Sciences

  • Founded: 2012
  • Location: Cambridge, MA
  • Employee range: 200 - 500
  • Clinical stage: Clin1b/Clin2a
  • Therapy area: ALS, FTD (partner: Takeda)
  • Drug types: NEU, GEN, MUS, LNG, HEP
  • Lead product: WVE-004
  • Product link: https://wavelifesciences.com/pipeline/
  • Funding: $70M stock Jun 2022; $100M stock Sep 2020


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Short description:

Stereopure oligonucleotides

Drug notes:

WVE-003 Clin1/Clin2 Huntington's disease (partner: Takeda); WVE-N531 Clin1/Clin2 DMD; WVE-006 Clin0 AATD - lung & liver disease; 3 undisclosed programs Clin0 spinocerebellar ataxia 3, CNS diseases

Long description:

Wave Life Sciences is developing novel oligonucleotide therapies for the treatment of rare genetic diseases. The company's PRISM platform enables the precise design, optimization, and production of stereopure oligonucleotides. Unlike traditional oligonucleotides, which are racemic mixtures of stereoisomers, stereopure oligonucleotides are composed of only one stereoisomer. This makes stereopure oligonucleotides more potent and less toxic than traditional oligonucleotides. Wave Life Sciences is using its PRISM platform to develop stereopure oligonucleotide therapies for a variety of rare genetic diseases, including Huntington's disease, Duchenne muscular dystrophy, and Batten disease. The company's lead product candidate, WVE-001, is a stereopure oligonucleotide therapy for the treatment of Huntington's disease.

Jobs:

WaVe Life Sciences
Senior Director, HR Business Partner
Cambridge, Massachusetts, Stati Uniti d'America|5 days ago
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WaVe Life Sciences
Research Informatics System Co-op (Fall 2024)
Lexington, Massachusetts, Stati Uniti d'America|6 days ago
WaVe Life Sciences
Research Associate, Biology
Cambridge, Massachusetts, Stati Uniti d'America|20 days ago
WaVe Life Sciences
Manufacturing Associate II
Lexington, Massachusetts, Stati Uniti d'America|25 days ago
WaVe Life Sciences
Manager/Sr. Manager, Medical Communications
Lexington, Massachusetts, Stati Uniti d'America|26 days ago
WaVe Life Sciences
Associate Director, Regulatory Affairs
Lexington, Massachusetts, Stati Uniti d'America|56 days ago
WaVe Life Sciences
Lab Systems Support Co-op (Fall 2024)
Lexington, Massachusetts, Stati Uniti d'America|69 days ago
WaVe Life Sciences
Senior Director, Head of Alliance Management
Cambridge, MA|81 days ago
WaVe Life Sciences
Clinical Trial Associate
Lexington, MA|88 days ago
WaVe Life Sciences
Scientist I/Scientist II, Pharmacometrics
Lexington, MA|97 days ago


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