WaVe Life Sciences

WaVe Life Sciences

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  • Founded: 2012
  • Location: Cambridge, MA
  • Employee range: 200 - 500
  • Clinical stage: Clin1b/Clin2a
  • Therapy area: ALS, FTD (partner: Takeda)
  • Drug types: NEU, GEN, MUS, LNG, HEP
  • Lead product: WVE-004
  • Funding: $70M stock Jun 2022; $100M stock Sep 2020


wavelifesciences.com

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Drug notes:

WVE-003 Clin1/Clin2 Huntington's disease (partner: Takeda); WVE-N531 Clin1/Clin2 DMD; WVE-006 Clin0 AATD - lung & liver disease; 3 undisclosed programs Clin0 spinocerebellar ataxia 3, CNS diseases

About:

Wave Life Sciences is developing novel oligonucleotide therapies for the treatment of rare genetic diseases. The company's PRISM platform enables the precise design, optimization, and production of stereopure oligonucleotides. Unlike traditional oligonucleotides, which are racemic mixtures of stereoisomers, stereopure oligonucleotides are composed of only one stereoisomer. This makes stereopure oligonucleotides more potent and less toxic than traditional oligonucleotides. Wave Life Sciences is using its PRISM platform to develop stereopure oligonucleotide therapies for a variety of rare genetic diseases, including Huntington's disease, Duchenne muscular dystrophy, and Batten disease. The company's lead product candidate, WVE-001, is a stereopure oligonucleotide therapy for the treatment of Huntington's disease.

Jobs:

WaVe Life Sciences
Director/Senior Director, Regulatory Affairs
Lexington, MA|15 days ago
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WaVe Life Sciences
Environmental Health & Safety Co-op (Spring 2025)
Lexington, MA|18 days ago
WaVe Life Sciences
Accounts Payable Co-op (Spring 2025)
Cambridge, MA|34 days ago
WaVe Life Sciences
Associate Director/Director, Medical Writer
Lexington, MA|56 days ago
WaVe Life Sciences
Process Technology Co-op
Lexington, MA|57 days ago
WaVe Life Sciences
Research informatics System Co-op (Spring 2025)
Cambridge, MA|63 days ago
WaVe Life Sciences
IT Systems Administrator Co-op (Spring 2025)
Lexington, MA|71 days ago
WaVe Life Sciences
IT Lab Systems Support Co-op (Spring 2025)
Lexington, MA|71 days ago
WaVe Life Sciences
Medicinal Chemistry Co-op (Spring 2025)
Cambridge, MA|71 days ago
WaVe Life Sciences
Oligonucleotide Analytical Chemistry Process Devel...
Lexington, MA|78 days ago
WaVe Life Sciences
Scientist I/Scientist II, Pharmacometrics
Lexington, MA|100+ days ago
WaVe Life Sciences
Associate Director, Data Management
Lexington, MA|Not provided


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