Vizgen

Next-generation spatially resolved, single-cell transcriptomics

Vizgen is building microscopy-based tools for spatial genomics. The last decade has seen rapid advances in the speed and scale of DNA sequencing. The next generation involves exploring an additional dimension - space. Vizgen has created MERSCOPE, a high multiplexing and high resolution in situ fluorescence microscopy platform for single-cell spatial genomics. The platform consists of a high-resolution microscope, microfluidics, automation protocols, and image processing/analysis software to conduct MERFISH, an in situ hybridization method that allows measuring the copy number and spatial distribution of hundreds to tens of thousands of RNA molecules in single cells.