Ventus Therapeutics

Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways

VENT-02 Clin1 neuro; VENT-01 Clin0 renal, cardiovascular, hepatic; VENT-05 RD undisclosed; VENT-04 RD various

Ventus Therapeutics uses structural biology and computational chemistry tools to address a wide range of diseases, including immunology, inflammatory, and neurological disorders. Their drug discovery platform models all protein conformations to identify druggable pockets in order to create a “blueprint” for developing small molecule therapeutics. Through their platform, Ventus can virtually screen libraries of compounds to identify molecules that resemble the “blueprint”and then optimize them for improved efficacy. They aim to address current limitations in industry. Their expertise in protein engineering, structure determination, and expression enables them to confront previously challenging targets like the inflammasome and nucleic acid sensing pathways.