TheWell Bioscience is advancing 3D biomimicking platforms to improve personalized medicines for every patient. To find effective therapeutics tools are required to mimic the human microenvironment. TheWell Bioscience is focused on driving advanced biomedicine with their 3D biomimicking platforms for precision medicine, cell therapy and bioprocessing. This involves the use of their xeno-free hydrogel system that can closely mimic the extracellular matrix, opening the door for clinical applications of 3D organoid models. TheWell Bioscience’s technology can be applied with cells from different sources, including patient-derived cells, enabling highly complicated organoid models to ve created.

TheWell Bioscience

 Sartorius Partners with TheWell Bioscience for Animal-Free Hydrogels & Bioinks 

✨ 𝗦𝘁𝗮𝗿𝘁 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝗲𝗻𝗱 𝗶𝗻 𝗺𝗶𝗻𝗱. 

🚀 Don't let the limitations of animal-based ECM hinder your research from advancing beyond the lab. 

VitroGel® is a xeno-free hydrogel system that offers an easier, faster, and more reproducible cell culture while having the ability to translate your assays toward advanced biomedicine.

✅ Xeno-free, biofunctional hydrogel system
✅ Room temperature operation. No ice bucket required.
✅ Supports various cell types and applications from 2D/3D, organoids, stem cells, MSCs, spheroids, functional assay, co-culture, and PDX and CDX in vivo
✅ 20-min protocol. Simple, quick, and easy-to-use. 

VitroGel® Biofunctional Hydrogels for various cell culture applications:
• VitroGel® Hydrogel Matrix
• VitroGel® ORGANOID (1-4)
• VitroGel® STEM
• VitroGel® MSC
• VitroGel® HEK293

 👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gxeUfg95
👉 Learn more about the Ready-To-Use VitroGel® Hydrogels:
       https://lnkd.in/gYMHZzyh

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gNgXJgmC

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invitro #invivo #oncology #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology

Adding depth to cell culture - Science

TheWell Bioscience Announces Launch of VitroGel® Organoid Recovery Solution for Fast and Safe Harvesting of Organoids/Cells with High Yields - PR Newswire

✨ 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹® 𝗥𝗚𝗗 𝗲𝗻𝗮𝗯𝗹𝗲𝗱 𝘁𝗵𝗲 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝗼𝗳 𝗹𝘆𝗺𝗽𝗵𝗼𝗺𝗼𝗶𝗱𝘀, 𝗮𝗻 𝗲𝘅 𝘃𝗶𝘃𝗼 𝗹𝘆𝗺𝗽𝗵𝗼𝗺𝗮 𝗺𝗼𝗱𝗲𝗹 𝘁𝗵𝗮𝘁 𝗽𝗿𝗲𝘀𝗲𝗿𝘃𝗲𝗱 𝘁𝗶𝘀𝘀𝘂𝗲 𝘀𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗲, 𝘃𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆, 𝗮𝗻𝗱 𝗰𝗲𝗹𝗹𝘂𝗹𝗮𝗿 𝗰𝗼𝗺𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻, 𝗳𝗮𝗰𝗶𝗹𝗶𝘁𝗮𝘁𝗶𝗻𝗴 𝗲𝗳𝗳𝗲𝗰𝘁𝗶𝘃𝗲 𝗱𝗿𝘂𝗴 𝘁𝗲𝘀𝘁𝗶𝗻𝗴 𝗮𝗻𝗱 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗼𝗳 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗲𝘀.

👏 Congratulations to Albert Santamaria-Martínez, et al. & Elisa Oricchio from EPFL (École Polytechnique Fédérale de Lausanne) on their paper “Development of patient-derived lymphomoids with preserved tumor architecture for lymphoma therapy screening”

👁️🗨️ Read the paper here: https://lnkd.in/eyw6cje6

This study introduces "lymphomoids," a novel ex vivo system designed for the preservation of small segments of human lymphoma tissue, facilitating therapeutic responses and evaluating tissue responses to small molecules while preserving histological, cellular, and molecular properties. The study collected 27 patient samples representing different lymphoma subtypes. The findings indicated that the impact of inhibitors in lymphomoids corresponded with the clinical responses of patients, thereby proposing lymphomoids as a novel ex vivo model for assessing anti-cancer therapeutic efficacy while also underscoring their capacity for rapid therapy sensitivity testing despite the limitation of long-term response evaluation.

🧫 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹® 𝗥𝗚𝗗 preserved lymphoid tissue architecture, which is often compromised in alternative models. This preservation was crucial for effective therapeutic response testing. VitroGel® RGD ensured cell viability of 70% to 80% during the initial week, which is essential for ex vivo model efficacy. By sustaining tissue structure and viability, VitroGel® RGD facilitated the assessment of lymphoid sensitivity to various clinically approved drugs, aligning with patient clinical outcomes.

👉 Learn more about the VitroGel® RGD used in the paper: https://lnkd.in/gY8JWK-A
👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gWqxDbaM

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gU-YsNcm

#3DCellCulture #biotech #biotechnology #cellculture #spheroids #matrigel #celltherapy #vitrogel #drugdiscovery #precisionmedicine #cellbiology #exvivo #cancerresearch #oncology #lymphomoids

𝗦𝘁𝗮𝘆 𝗼𝗻 𝘁𝗵𝗲 𝗻𝗶𝗰𝗲 𝗹𝗶𝘀𝘁 𝘁𝗵𝗶𝘀 𝘀𝗲𝗮𝘀𝗼𝗻! 🎅 

✨ Choose a sustainable alternative to animal-based ECM and support your Corporate Social Responsibility goals. Discover the possibilities with the VitroGel® system today! 

👉 Read over 210+ Publications: https://lnkd.in/gRkrqC3Z
👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gEyAQmPp

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/g2FMuftX
#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invivo #oncology #drugdiscovery #precisionmedicine #cellbiology #corporatesocialresponsibility #sustainability #socialimpact

✨ 𝗘𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲 𝗾𝘂𝗶𝗰𝗸 𝗮𝗻𝗱 𝗲𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝗰𝗲𝗹𝗹/𝗼𝗿𝗴𝗮𝗻𝗼𝗶𝗱 𝗿𝗲𝗰𝗼𝘃𝗲𝗿𝘆 𝗳𝗿𝗼𝗺 𝗮𝗻𝗶𝗺𝗮𝗹-𝗯𝗮𝘀𝗲𝗱 𝗘𝗖𝗠 𝘄𝗶𝘁𝗵 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹® 𝗢𝗿𝗴𝗮𝗻𝗼𝗶𝗱 𝗥𝗲𝗰𝗼𝘃𝗲𝗿𝘆 𝗦𝗼𝗹𝘂𝘁𝗶𝗼𝗻.

VitroGel® Organoid Recovery Solution is a non-enzymatic cell harvesting solution for high recovery of cells/organoids with high viability from cells cultured in an animal-based ECM or VitroGel® for downstream analysis and expansion.

✅  2-minute dissociation of animal-based ECM.
✅  High recovery and cell viability.
✅  Enzyme-free, stable formulation. Long shelf life. 

👉 Learn more about VitroGel® Organoid Recovery Solution: https://lnkd.in/g79wj5Dw
👉 Learn how cell harvesting works: https://lnkd.in/gyd2Kf8c

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gb79SHnD

#3DCellCulture #biotech #biotechnology #cellculture #organoids #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #oncology #drugdiscovery #precisionmedicine #cellbiology

Marcel Janis Beha, Kim, J.-C., San Hae Im, Kim, Y., Yang, S., Ju Hee Lee, Yu Ri Nam, Lee, H., Park, H.-S., & Hyun Jung Chung. (2023). Bioorthogonal CRISPR/Cas9‐Drug Conjugate: A Combinatorial Nanomedicine Platform. Advanced Science, https://doi.org/10.1002/advs.202302253

✨ 𝗖𝘆𝘁𝗼𝟯𝗗® 𝗟𝗶𝘃𝗲-𝗗𝗲𝗮𝗱 𝗔𝘀𝘀𝗮𝘆 𝗞𝗶𝘁 𝗽𝗿𝗼𝘃𝗶𝗱𝗲𝗱 𝗮 𝗿𝗲𝗹𝗶𝗮𝗯𝗹𝗲 𝗺𝗲𝘁𝗵𝗼𝗱 𝘁𝗼 𝗾𝘂𝗮𝗻𝘁𝗶𝗳𝘆 𝘁𝗵𝗲 𝗲𝗳𝗳𝗲𝗰𝘁𝘀 𝗼𝗳 𝗛𝗼𝗻𝗼𝗸𝗶𝗼𝗹 𝗮𝗻𝗱 𝗠𝗮𝗴𝗻𝗼𝗹𝗼𝗹 𝗼𝗻 𝗛𝗡𝗦𝗖𝗖 𝘃𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗶𝗻 𝗮 𝟯𝗗 𝗰𝘂𝗹𝘁𝘂𝗿𝗲 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁.

👏 We would like to recognize the achievement by Robert Kleszcz, et al. & Jarosław Paluszczak from Poznan University of Medical Sciences on their paper “Honokiol Is More Potent than Magnolol in Reducing Head and Neck Cancer Cell Growth”

👁️🗨️ Read the paper here: https://lnkd.in/gzXc9fbA

The study was designed to investigate the anti-cancer properties of honokiol (HON) and magnolol (MAG) on head and neck squamous cell carcinoma (HNSCC) cell lines. The study focused on comparing the effect of both compounds on cisplatin-sensitive and cisplatin-tolerant cells, particularly regarding cell viability, cell cycle, apoptosis, and gene expression. The results indicated that HON was more effective than MAG at reducing cell viability, especially in three-dimensional cultures, and both compounds were noted to lower viability in cisplatin-tolerant FaDu cells, potentially through cell cycle regulation and the BIRC5 gene expression.

🧪 𝗖𝘆𝘁𝗼𝟯𝗗® 𝗟𝗶𝘃𝗲-𝗗𝗲𝗮𝗱 𝗔𝘀𝘀𝗮𝘆 𝗞𝗶𝘁 contributed significantly to the results by providing a reliable method to quantify the effects of HON and MAG on cell viability in a 3D culture environment. This approach allowed to observe the more pronounced cytotoxic effects of HON compared to MAG, particularly in the 3D cultures, which are considered to better represent the 𝘪𝘯 𝘷𝘪𝘷𝘰 tumor conditions. The assay kit capability to differentiate between viable and non-viable cells via fluorescence yielded precise and measurable information regarding the effectiveness of the compounds in inhibiting cancer cell proliferation.

👉 Learn more about the Cyto3D® Live-Dead Assay Kit used in the paper: https://lnkd.in/geAQV2y3
👉 Learn more our xeno-free VitroGel® hydrogels which allow you to translate your research towards advanced biomedicine: https://lnkd.in/gNMxaUgu

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gnDFupbc

#3DCellCulture #biotech #biotechnology #cellculture #spheroids #matrigel #celltherapy #vitrogel #drugdiscovery #precisionmedicine #cellbiology #invivo #cancerresearch #oncology

 TheWell Bioscience on LinkedIn: #cellularresearch #invitromodels #researchefficiency 

 Sartorius on LinkedIn: Sartorius and TheWell Bioscience partner to enable more accurate… 

A Bioprinting World Map - 3DPrint.com

Sartorius and TheWell Bioscience partner to enable more accurate predictions in drug discovery - BioProcess Insider

Mori, H., Saeki, K., Chang, G., Wang, J., Wu, X., Hsu, P.-Y., Kanaya, N., Wang, X., Somlo, G., Nakamura, M., Bild, A., & Chen, S. (2021). Influence of Estrogen Treatment on ESR1+ and ESR1− Cells in ER+ Breast Cancer: Insights from Single-Cell Analysis of Patient-Derived Xenograft Models. Cancers, 13(24), 6375. https://doi.org/10.3390/cancers13246375

8 Top 3D Bioprinting Startups Impacting The Biotechnology Industry - StartUs Insights

🥳 𝗛𝗮𝗽𝗽𝘆 𝗡𝗲𝘄 𝗬𝗲𝗮𝗿 𝗳𝗿𝗼𝗺 𝗧𝗵𝗲𝗪𝗲𝗹𝗹 𝗕𝗶𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲! 🎊

As we step into 2025, we remain committed to advancing the future of 3D cell culture research. Together with our incredible partners and researchers, we are excited to accelerate innovation, drive breakthroughs, and support discoveries that will shape the future of biomedicine. 

Here's to a year of continued progress and new possibilities for a sustainable 3D cell culture!

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #cancerresearch #celltherapy #vitrogel #oncology #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology

💡 𝗦𝘁𝗮𝗿𝘁 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝗲𝗻𝗱 𝗶𝗻 𝗺𝗶𝗻𝗱.

🚀 Don't let animal-based ECM limit your cell culture research progress. The xeno-free VitroGel® hydrogel helps translate your cell culture assays toward advanced biomedicine.

✨ One of the many advantages of VitroGel® over animal-based ECM is its stability at room temperature. VitroGel® remains liquid at room temperature, and its hydrogel polymerization is independent of temperature and does not require a cross-linking agent. 

✅ Stable at room temperature. No unexpected gelation due to temperature fluctuation.
✅ No cross-linking reagent required.
✅ Simple, fast, and easy to use.

👉 Discover how gelation works in VitroGel®: https://lnkd.in/gGrAmV8v
👉 Try the VitroGel® Starter Kit today! https://lnkd.in/g-b7s-t2

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/g5jrfrVM


#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invitro #oncology #invivo #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology

✨ 𝗦𝗲𝗮𝘀𝗼𝗻'𝘀 𝗚𝗿𝗲𝗲𝘁𝗶𝗻𝗴𝘀 𝗳𝗿𝗼𝗺 𝗧𝗵𝗲𝗪𝗲𝗹𝗹 𝗕𝗶𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲! ✨
 
As 2024 draws to a close, we want to express our heartfelt gratitude to all the researchers, collaborators, and distributors worldwide who have joined us in our mission to improve patient lives. Your support has been an invaluable gift for 3D cell culture research, inspiring our continued innovation and growth.

🌟🎄 Wishing you a Merry Christmas and a joyful holiday season and a sincere thank you for being an essential part of our journey. We look forward to an even brighter 2025 together!

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #cancerresearch #celltherapy #vitrogel #oncology #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology

🚀 𝗗𝗼𝗻'𝘁 𝗹𝗲𝘁 𝗮𝗻𝗶𝗺𝗮𝗹-𝗯𝗮𝘀𝗲𝗱 𝗘𝗖𝗠 𝗸𝗲𝗲𝗽 𝘆𝗼𝘂𝗿 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻 𝘁𝗵𝗲 𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗼𝗿𝘆. 𝗧𝗵𝗲 𝘅𝗲𝗻𝗼-𝗳𝗿𝗲𝗲 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹® 𝗰𝗮𝗻 𝘁𝗿𝗮𝗻𝘀𝗹𝗮𝘁𝗲 𝘆𝗼𝘂𝗿 𝗰𝗲𝗹𝗹 𝗰𝘂𝗹𝘁𝘂𝗿𝗲 𝗮𝘀𝘀𝗮𝘆 𝘁𝗼𝘄𝗮𝗿𝗱𝘀 𝗮𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗯𝗶𝗼𝗺𝗲𝗱𝗶𝗰𝗶𝗻𝗲. 
 
✨ VitroGel® hydrogel is stable at room temperature and does not require dry ice shipping, eliminating the use of foam boxes and preventing additional CO2 emissions making it a more sustainable alternative to animal-based ECM.

✅ Stable at room temperature. 
✅ Ships at ambient temperature. No dry ice required.
✅ Sustainable and more environment-friendly.

👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gPuZjsQ2
👉 Try the VitroGel® Starter Kit today! https://lnkd.in/gxxU9jgv

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gnDFupbc

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invitro #invivo #oncology #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology #corporatesocialresponsibility #sustainability #socialimpact

Protected: TheWell Bioscience 2024 Innovations for Advancing 3D Cell Culture

✨ 𝗦𝘁𝗮𝗿𝘁 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝗲𝗻𝗱 𝗶𝗻 𝗺𝗶𝗻𝗱.  

Go beyond animal-based ECM and discover the 20+ advantages for your cell 3D cell culture with VitroGel®, offering easier, faster, and more reproducible cell culture assays while having the ability to translate them towards advanced biomedicine

✅ Xeno-free, biofunctional hydrogel system.
✅ Room temperature operation. No ice bucket required.
✅ Supports various cell types and applications from 2D/3D, organoids, stem cells, MSCs, spheroids, functional assay, co-culture, and PDX and CDX in vivo.
✅ 20-min protocol. Simple, quick, and easy-to-use. 

👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gUd4447z
👉 Learn more about VitroGel®: https://lnkd.in/gZFfDPZs

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/g9enGbgu

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invivo #oncology #drugdiscovery #precisionmedicine #cellbiology #invitro

📢 𝗔𝗩𝗔𝗜𝗟𝗔𝗕𝗟𝗘 𝗙𝗢𝗥 𝗔 𝗟𝗜𝗠𝗜𝗧𝗘𝗗 𝗧𝗜𝗠𝗘!

✨ 𝗦𝘁𝗮𝗿𝘁𝗶𝗻𝗴 𝗮𝘁 $𝟳𝟵, kickstart your 3D cell culture/organoid research and move beyond animal-based ECMs with our VitroGel® Starter Kit for an easier, faster, and more consistent cell culture.

Ideal for 2D/3D cultures, organoids, spheroids, co-culture, and PDX/CDX in vivo studies, the VitroGel® Starter Kit provides a complete workflow from 3D model establishment to downstream analysis.

Kit includes hydrogel of choice:
•  VitroGel® Hydrogel Matrix or VitroGel® ORGANOID-3.
   ✅ Cost-efficient solution to kickstart your cell culture research.
   ✅ 20-minute protocol. Easy-to-use, Room temperature operation.
   ✅ No batch-to-batch variability for reproducible results.
•  Cyto3D® Live-Dead Assay Kit for live-dead cell analysis.
•  VitroGel® Cell Recovery Solution for non-enzymatic cell harvesting.
• VitroPrime™ Spread-Attach Plate.  Choose from 6-well, 12-well, 24-well, 48-well or 96-well.

Grab your kit now while supplies last!
👉 Learn more about VitroGel® Starter Kits: https://lnkd.in/gNxh8duC

✉️ Contact us or connect with your sales rep for more information!

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Looking for our products outside the US? Here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gma7552w

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invivo #invitro #oncology #drugdiscovery #precisionmedicine #cellbiology

Global Organoids and Spheroids Market Set for Remarkable Growth, Reaching USD 7.70 Billion by 2034 with a CAGR of 23.12% - Yahoo Finance

Di Donato, M., Galasso, G., Giovannelli, P., Sinisi, A. A., Migliaccio, A., & Castoria, G. (2021). Targeting the Nerve Growth Factor Signaling Impairs the Proliferative and Migratory Phenotype of Triple-Negative Breast Cancer Cells. Frontiers in Cell and Developmental Biology, 9. https://doi.org/10.3389/fcell.2021.676568

Protected: Celebrating Growth: TheWell Bioscience moves to a new facility!

Kim, A.-Y., Yoon, Y. N., Leem, J., Lee, J.-Y., Jung, K.-Y., Kang, M., Ahn, J., Hwang, S.-G., Oh, J. S., & Kim, J.-S. (2020). MKI-1, a Novel Small-Molecule Inhibitor of MASTL, Exerts Antitumor and Radiosensitizer Activities Through PP2A Activation in Breast Cancer. Frontiers in Oncology, 10. https://doi.org/10.3389/fonc.2020.571601

🚀 VitroGel® helps achieve a fast, easy, and consistent 3D cell culture at 𝗿𝗼𝗼𝗺 𝘁𝗲𝗺𝗽𝗲𝗿𝗮𝘁𝘂𝗿𝗲 𝗼𝗽𝗲𝗿𝗮𝘁𝗶𝗼𝗻!
 
✨ Work confidently at room temperature as VitroGel® hydrogel remains liquid and free flowing. Unlike animal-based ECM, the hydrogel polymerization is not affected by temperature, nor does it require a cross-linking reagent.
 
✅ Stable at room temperature. No unexpected gelation due to temperature fluctuation.
✅ Easy-to-use, no cross-linking reagent required.
✅ Ensures consistent and reproducible results.

👉 Discover how gelation works in VitroGel®: https://lnkd.in/gQ7NBaFS
👉 Try a VitroGel® Starter Kit today to discover the many advances of the xeno-free VitroGel® hydrogel over animal-based ECM for an easier and more reproducible 3D cell culture. https://lnkd.in/g_pbn5RV

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gkzttiT3

#3DCellCulture #biotech #biotechnology #cellculture #organoids #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #oncology #drugdiscovery #precisionmedicine #cellbiology #invitro #invivo

🚀 𝗘𝗹𝗲𝘃𝗮𝘁𝗲 𝘆𝗼𝘂𝗿 𝗰𝗲𝗹𝗹 𝗰𝘂𝗹𝘁𝘂𝗿𝗲 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗮𝗻𝗱 𝗰𝗼𝗻𝘁𝗿𝗶𝗯𝘂𝘁𝗲 𝘁𝗼 𝗮 𝗺𝗼𝗿𝗲 𝘀𝘂𝘀𝘁𝗮𝗶𝗻𝗮𝗯𝗹𝗲 𝗳𝘂𝘁𝘂𝗿𝗲 𝘄𝗶𝘁𝗵 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹®.

🔬This 2025, join over 1,000 research labs worldwide that are using VitroGel® to advance cell culture models from 2D/3D, organoids, stem cells, MSCs, spheroids, functional assay, co-culture, and PDX and CDX 𝘪𝘯 𝘷𝘪𝘷𝘰 applications, all while making a positive impact on our planet.

What’s your resolution for 2025? Share below! 👇

👉 Learn more about VitroGel®: https://lnkd.in/gVRj9n8U
👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gGMY6M2M

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gTBaNAgr

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #cancerresearch #celltherapy #vitrogel #oncology #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology #newyear #newyearresolution #2025

🎁✨ 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹®: 𝗧𝗵𝗲 𝗣𝗲𝗿𝗳𝗲𝗰𝘁 𝗚𝗶𝗳𝘁 𝗳𝗼𝗿 𝗬𝗼𝘂𝗿 𝟯𝗗 𝗖𝗲𝗹𝗹 𝗖𝘂𝗹𝘁𝘂𝗿𝗲 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵! 

🎄 With VitroGel®, unwrap new possibilities in 3D cell culture and go beyond the limitations of animal-based ECM. 

Achieve easier, faster, and more consistent cell culture—complete with lab automation capabilities and the ability to translate cell culture assay towards advanced biomedicine.

✅ Xeno-free, biofunctional hydrogel system.
✅ Room temperature operation. No ice bucket required.
✅ Supports various cell types and applications from 2D/3D, organoids, stem cells, MSCs, spheroids, functional assay, co-culture, and PDX and CDX in vivo.
✅ 20-min protocol. Simple, quick, and easy-to-use. 

👉 Try the VitroGel® Starter Kit today! https://lnkd.in/gW5FkbeH
👉 Discover the many advantages of the xeno-free VitroGel® hydrogels over animal-based ECM: https://lnkd.in/gyZPXX-v

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gREQeDVr

#3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invitro #invivo #oncology #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology

Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening | Scientific Reports - Nature.com

 Sartorius Group’s Agreement And Minority Investment With TheWell Bioscience Inc. 

✨ 𝗩𝗶𝘁𝗿𝗼𝗚𝗲𝗹® 𝗢𝗥𝗚𝗔𝗡𝗢𝗜𝗗 𝗽𝗹𝗮𝘆𝗲𝗱 𝗮 𝗰𝗿𝗶𝘁𝗶𝗰𝗮𝗹 𝗿𝗼𝗹𝗲 𝗶𝗻 𝘁𝗵𝗲 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝗼𝗳 𝗮 𝟯𝗗 𝘃𝗮𝘀𝗰𝘂𝗹𝗮𝗿 𝗺𝗼𝗱𝗲𝗹 𝘁𝗵𝗮𝘁 𝗽𝗿𝗼𝘃𝗶𝗱𝗲𝗱 𝗱𝗲𝗲𝗽𝗲𝗿 𝗶𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻𝘁𝗼 𝘁𝗵𝗲 𝗺𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗯𝘆 𝘄𝗵𝗶𝗰𝗵 𝗣𝗠𝟭𝟬 𝗲𝘅𝗽𝗼𝘀𝘂𝗿𝗲 𝗶𝗻𝗰𝗿𝗲𝗮𝘀𝗲𝘀 𝘁𝗵𝗲 𝗿𝗶𝘀𝗸 𝗼𝗳 𝗵𝗲𝗺𝗼𝗿𝗿𝗵𝗮𝗴𝗶𝗰 𝘀𝘁𝗿𝗼𝗸𝗲.

👏 An excellent paper by Chae Hwan Lee, et al. & Jin Hyup Lee from Korea University on their paper “Mechanistic insight into airborne particulate matter PM10 as an environmental hazard for hemorrhagic stroke: Evidence from in vitro and in vivo studies”

👁️🗨️Read the paper here: https://lnkd.in/gDKdzA6t

The study focused on understanding how PM10 airborne particles elevate hemorrhagic stroke (HS) risk by utilizing 3D spheroid culture and in vivo mouse experiments to replicate the interactions between brain vascular endothelial (BVEC) and vascular smooth muscle cells (VSMC). The study indicated that PM10 exposure causes necroptotic death of VSMC through FasL inflammatory cytokine from BVEC, linked to oxidative stress and aluminum-induced DNA damage, emphasizing the role of ATM-NF-κB signaling. This study provides molecular evidence establishing a direct association between PM10 pollution and an elevated risk of stroke, particularly HS.

🧫 VitroGel® ORGANOID facilitated the creation of a 3D vascular spheroid model by serving as a hydrogel scaffold that enables cells to grow and arrange into tissue-like structures, essential for examining intricate cell interactions in a physiologically relevant context. This model enabled a precise examination of PM10 impact on the cerebrovascular system and facilitated the observation of necroptotic manifestations in VSMC and the role of BVEC in mediating these effects through FasL signaling.

👉 Learn more about the VitroGel® ORGANOID used in the paper: https://lnkd.in/gmN-QJmQ
👉 Learn more on our xeno-free VitroGel® hydrogels which allow you to translate your research to clinical applications: https://lnkd.in/gH4ECiNQ

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For orders outside the US, here are a few of our distributors:
Tebubio, BioCat GmbH (part of AddLife), Dakewe Biotech Co., Genomax Technologies, Bio-Science Kft./Ltd. - Hungary, Immuno Diagnostic Oy, REGEMAT 3D, Sciencewerke Pte Ltd, SVEN BioLabs s.r.o., 300K Solutions, LAB-A-PORTER, The Biotech Company
For more distributors: https://lnkd.in/gU5SvSHa

#3DCellCulture #biotech #biotechnology #cellculture #organoids #spheroids #matrigel #cancerresearch #celltherapy #vitrogel #oncology #drugdiscovery #precisionmedicine #cellbiology #invivo #invitro #cerebrovascular

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