Talis Biomedical is developing diagnostic tests for highly accurate and rapid disease detection. To battle against infectious diseases, such as COVID-19, rapid and timely diagnosis is needed. Talis has been using expertise in design, engineering and technology to create high quality products for point-of-care disease detection. This includes their Talis One technology that performs isothermal nucleic acid amplification tests within 30 minutes for accurate and sensitive results. The technology has been adapted for both DNA and RNA amplification and works with nasal specimen collection. Talis continues to optimize the performance of their instruments and most recently created the Talis One COVID-19 test system that has the potential to become a leading SARS-CoV-2 and emerging variants detecting device.