Surface Oncology is developing cancer therapies that function by targeting the immune-suppressive tumor microenvironment. Many cancer cells resist immune-cell clearance by fostering an immune-suppressive microenvironment. To overcome this, Surface Oncology is developing multiple antibody immunotherapy candidates focused on enhancing the innate and adaptive immune responses to trigger a more robust immunologic response. Surface is researching four key areas of immune modulators that range from activating macrophages and natural killer cells, to blocking suppressive cell signaling molecules. This has enabled Surface to build their diverse pipeline with many products in Phase 1 trials for various cancers.

<p>Surface Oncology is developing cancer therapies that function by targeting the immune-suppressive tumor microenvironment. Many cancer cells resist immune-cell clearance by fostering an immune-suppressive microenvironment. To overcome this, Surface Oncology is developing multiple antibody immunotherapy candidates focused on enhancing the innate and adaptive immune responses to trigger a more robust immunologic response. Surface is researching four key areas of immune modulators that range from activating macrophages and natural killer cells, to blocking suppressive cell signaling molecules. This has enabled Surface to build their diverse pipeline with many products in Phase 1 trials for various cancers.</p>


Surface Oncology

Founded: 2015
Location: Cambridge, MA
Employee range: 50 - 200
Clinical stage: Clin2
Therapy area: hepatocellular carcinoma, NSCLC
Drug types: ONC
Lead product: SRF388
Funding: $119.5M IPO Apr 2018

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