Shasqi

Local Drug Activation

Shasqi is using click chemistry technology to develop cancer therapies. Click chemistry refers to a highly selective set of chemical reactions that have a diversity of applications. Shasqi is leveraging click chemistry to get active cancer treatments to tumors using their CAPAC (Click Activated Protodrugs Against Cancer) platform. The approach works by targeting a click chemistry reagent to the tumor where it activates a second agent, a systemically infused protodrug. Activation unlocks a powerful localized therapy at the tumor site minimizing toxic side effects. Shasqi is currently conducting clinical trials to assess the safety, tolerability and efficacy of their approach in patients with advanced solid tumors.