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Shape Therapeutics

Founded: 2018

Location: Seattle, WA

Employee range: 50 - 200

Clinical stage: RD

Therapy area: Genetic diseases

Drug types: GEN

Lead product: Undisclosed

Product link: https://shapetx.com/

Funding: $112M B Jul 2021; $35.5M A Nov 2019

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Short description:

RNA-editing gene therapy

Drug notes:

Long description:

Shape Therapeutics is developing RNA technologies to shape the future of gene therapies. To achieve this, Shape has built their gene therapy platform, comprising RNAskip, RNAfix and RNAswap payload technologies and tissue-specific AAVid delivery technology. Data output from the platform is then incorporated into Shape’s AI engine, where data drives decisions to select the next gene therapies that are scalable and curative for many diseases. This combination of cutting-edge science and drug development expertise is enabling Shape to advance breakthroughs in RNA editing to correct mutations, fine-tune gene expression and modulate protein interactions. Currently, Shape is focusing on therapies for Parkinson’s disease and the ocular disorder Stargardt disease.