• Founded: 2021
  • Location: South SF, CA
  • Employee range: 0 - 0
  • Clinical stage: Clin0
  • Therapy area: Hypoparathyroidism
  • Drug types: END, IMM, OPH, NEU, PN
  • Lead product: Undisclosed
  • Product link:
  • Funding: $150M B Jul 2023; $100M A Jan 2022
  • Investors: Third Rock Ventures, Samsara BioCapital, BVF Partners, Invus Financial Advisors, Catalio Capital Management, Casdin Capital, Logos Capital, RA Capital Management, Deep Track Capital, Goldman Sachs Asset Management, Vertex Ventures HC, Mirae Asset Financial Group, Driehaus Capital Management, Woodline Partners LP, Soleus Capital

job board

Short description:

GPCR Drug Discovery

Drug notes:

Undisclosed Clin0 Grave's disease, thyroid eye disease; 3 CNS disorders, inflammatory & pain disorders, undisclosed

Long description:

Septerna is developing drugs against G-protein coupled receptors (GPCRs). GPCRs are found at the cell membrane and have proven to be the most ‘druggable’ class of proteins. However, many remain ‘undruggable’. Septerna is addressing this problem using their Native Complex platform to design a new era of GPCR-targeted medicines. The platform recapitulates the native structure, function and dynamics of GPCRs, thus enabling structure-based drug design and large-scale screening. Drug hits are further examined with Cryo-EM and optimized through in silico approaches. Due to the prolific nature of GPCRs, Septerna’s diversified portfolio spans multiple therapeutic areas.


Director, IT (Biotech/Life Science)
South San Francisco, CAOn-site|11 days ago
Director, Clinical Operations
South San Francisco, CAOn-site|11 days ago
Senior Scientist/Staff Scientist, DMPK
South San Francisco, CAOn-site|27 days ago
Senior Staff Scientist/Associate Director, Disease...
South San Francisco, CAOn-site|58 days ago
Summer Research Intern - Biochemistry/Chemical Bio...
South San Francisco, CAOn-site|64 days ago
Senior Research Associate/Associate Scientist, Dis...
South San Francisco, CA/ On-site|100+ days ago

© 2024 Work In Biotech LLC
Personal data

Terms of Service

Privacy Policy