Reverie Labs is pioneering technology to develop next-generation cancer therapies. Computational chemistry and machine learning provide new tools for drug discovery. Reverie is using these methods to develop small molecule kinase inhibitors to treat cancer. The process involves prediction of important molecular properties for on-target drug binding, screening millions of compounds in their virtual libraries for hit identification and molecular dynamics to understand the energetics of bound ligands to their protein targets. Reverie also uses algorithmic molecular generation to ensure selective molecules are synthesizable, stable and tissue-penetrant. With this approach, Reverie will advance a pipeline of tissue-penetrant kinase inhibitors for oncology targets.

<p>Reverie Labs is pioneering technology to develop next-generation cancer therapies. Computational chemistry and machine learning provide new tools for drug discovery. Reverie is using these methods to develop small molecule kinase inhibitors to treat cancer. The process involves prediction of important molecular properties for on-target drug binding, screening millions of compounds in their virtual libraries for hit identification and molecular dynamics to understand the energetics of bound ligands to their protein targets. Reverie also uses algorithmic molecular generation to ensure selective molecules are synthesizable, stable and tissue-penetrant. With this approach, Reverie will advance a pipeline of tissue-penetrant kinase inhibitors for oncology targets.</p>


Reverie Labs

Founded: 2017
Location: Cambridge, MA
Employee range: 11 - 50
Clinical stage: Clin0
Therapy area: Oncology
Drug types: ONC
Lead product: RVL-101
Funding: $25M A Feb 2021

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