Relay Therapeutics is identifying drugs to alter protein kinetics to treat patients with cancer and genetic diseases. Proteins are not stationary - they move, and how they move can inform function and disease. Using their Dynamo platform, Relay is visualizing protein motions in HD movies and pioneering Motion-based Drug Design. The platform combines both deep structural understanding and chemical biology insights with AI and physics-based simulations to harness protein dynamics. With this, Relay can then develop unique hypotheses for how best to modulate a protein’s behavior and identify potential novel allosteric binding sites for therapeutics. Relay’s pipeline includes several promising product candidates in early and preclinical stages.