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Small Molecules to Target ncRNA Biology
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Redona Therapeutics is developing small molecule therapies to target nucleic acid regulators. Processing and sensing of nucleic acids can become dysregulated, developing into serious diseases like cancer and autoimmune disease. This method of targeting enzymes that regulate RNA or DNA can effect several disease hallmarks rather than just a single pathway. These regulators may be involved in critical cellular processes like DNA or RNA stability, sensing, replication, repair, or RNA splicing. Redona aims to restore these dysregulated processes in severe disease, producing a therapeutic benefit to patients. Redona also hopes to partner with others in order to determine other applications of their technologies outside of cancer and autoimmune disease.
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