Pretzel Therapeutics

Pretzel Therapeutics is leading the way for a new era of life-changing medicines for mitochondrial diseases. Mitochondrial diseases arise when there is an cellular imbalance of mutated, dysfunctional mitochondria to healthy mitochondria. Pretzel is designing a portfolio of programs to upregulate the healthy levels of mitochondrial DNA (mtDNA) with their compounds showing a dose-dependent increase in mtDNA production. By applying their technology to various organs and tissues, Pretzel has the potential for multi-organ therapeutic benefit for a wide range of mitochondrial diseases and other diseases associated with aging and neurodegeneration.

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