Nuanced Health is revolutionizing drug development to discover and develop precision medicines. Human biology is heterogeneous with the environment and behavior shaping the way people maintain homeostasis, fight disease and respond to treatment. Nuanced Health is using next-generation preclinical models that recreate the heterogeneity of human populations to interrogate the environmental imprint on human biology. These models involve humanizing the mouse microbiome, creating a drug discovery and development platform that captures the microbial diversity that is central to human health outcomes. By repeating this process at scale with many human microbiome samples, Nuanced Health has generated a preclinical platform consisting of hundreds of humanized mouse lines. Nuanced is initially using their models to test drugs in oncology and obesity.

Nuanced Health

Founded: 2020
Location: Los Angeles, CA
Employee range: 1-50
Funding: not disclosed

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