Nautilus Biotechnology is unlocking the proteome to enable fundamental advances across human health and medicine. There is a wealth of information about human biology that is held within the proteome - the collection of proteins and their abundance in a cell. However, techniques to access this information have until now been limiting. Nautilus has created the first, large-scale, single-molecule platform to comprehensively quantify >95% of the proteome. The platform uses a protein array and fluorescent affinity-probes and was created by integrating innovations in computer science, engineering and biochemistry to deliver extreme sensitivity and scale. With this technology, biological research can lead to a better understanding of human diseases.