Morphic Therapeutic

Oral Integrin Drugs

4 undisclosed programs RD/Clin0 GI conditions, solid tumors, fibrotic conditions, PAH, undisclosed

Morphic Therapeutic is developing a new generation of oral integrin therapies to treat autoimmune, cardiovascular and metabolic diseases. Integrins are receptors found at the cell membrane and are involved in many cellular processes by signaling bi-directionally. Malfunctions in the integrins are linked with disease. Using their proprietary MInT drug discovery platform and knowledge from integrin research leaders, Morphic is in the position to target all 24 known human integrins to stabilize their conformation or to activate or inhibit their activity to modify disease. One molecule (MORF-057) is already in Phase I clinical trials for inflammatory bowel disease.