Krystal Biotech

Krystal Biotech

  • Founded: 2015
  • Location: Pittsburgh, PA
  • Employee range: 50 - 200
  • Clinical stage: Clin3
  • Therapy area: Dystrophic epidermolysis bullosa (ODD, Fast track)
  • Drug types: DRM, RAR, GEN, PED, AES, LNG
  • Lead product: B-VEC
  • Product link: https://www.krystalbio.com/focus/pipeline/
  • Funding: $160M stock May 2023


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Short description:

Gene Therapy

Drug notes:

KB105 Clin1/Clin2 TGM1-deficient ARCI (ODD, fast track); KB407 Clin1 cystic fibrosis (ODD); KB301 Clin1 undisclosed; KB104 Clin0 Netherton syndrome; KB5XX Clin0 skin conditions; KB408 Clin0 alpha-1 antitrypsin deficiency; 6+ additional programs RD/Clin0 undisclosed

Long description:

Krystal Biotech is developing gene therapies to address skin diseases. Many debilitating skin diseases lack effective treatments. Krystal is solving this by introducing therapeutic genes into patients with skin diseases. To achieve this, Krystal is using their patented gene therapy platform, Skin TARgeted Delivery (STAR-D), that consists of an engineered HSV-1 vector optimized for gene transfer in skin. The engineered HSV-1 vector is replication-defective and non-integrating such that it can penetrate a broad range of skin cells without posing a risk to genome disruption. The therapies are designed to be administered topically allowing direct and repeat delivery of therapeutic genes to the skin. Krystal’s most advanced therapy for Epidermolysis Bullosa is in Phase 3 trials.

Jobs:

Krystal Biotech
QC Microbiology Technician (Cleanroom)
Pittsburgh, PA|3 days ago
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Krystal Biotech
Purchasing Associate
Pittsburgh, PA|5 days ago
Krystal Biotech
Custodian / Cleanroom Facility Support
Pittsburgh, PA|10 days ago
Krystal Biotech
Manufacturing / Bioprocess Support Technician
Pittsburgh, PA|10 days ago
Krystal Biotech
Director of Patient Marketing
Remote|11 days ago
Krystal Biotech
Biotech Facility Maintenance Technician
Moon Township, PA|12 days ago
Krystal Biotech
Area Director, West
Remote|16 days ago
Krystal Biotech
Quality Control Analyst II
Pittsburgh, PA|17 days ago
Krystal Biotech
Medical Director, France
Remote|18 days ago
Krystal Biotech
Calibration / Maintenance Technician
Moon Township, PA|23 days ago
Krystal Biotech
Senior Manager / Associate Director of Corporate C...
Pittsburgh, PA|25 days ago
Krystal Biotech
IT Desktop Support Technician
Pittsburgh, PA|26 days ago
Krystal Biotech
Director of HCP Marketing
Remote|27 days ago
Krystal Biotech
Regional Gene Therapy Consultant - Gulf Coast
Remote|37 days ago
Krystal Biotech
Maintenance Technician
Pittsburgh, PA|40 days ago
Krystal Biotech
Project Manager / Engineer
Pittsburgh, PA|67 days ago
Krystal Biotech
Quality Assurance Associate
Moon Township, PA|67 days ago
Krystal Biotech
Bioprocess Engineer
Moon Township, PA|69 days ago
Krystal Biotech
Manufacturing Support Technician
Pittsburgh, PA|100+ days ago
Krystal Biotech
Process Validation Associate / Engineer
Pittsburgh, PA|100+ days ago


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