Keros Therapeutics

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Founded: 2015

Location: Lexington, MA

Employee range: 50 - 200

Clinical stage: Clin2

Therapy area: Myelodysplastic syndromes

Drug types: ONC, HEM, MUS

Lead product: KER-050

Funding: $110M IPO Apr 2020; $23M B Jan 2019; $11M A 2016

Investors: Pontifax, Arkin Bio Ventures, Partners Innovation Fund, Medison Pharma, Global Health Sciences Fund

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Drug notes:

Also Clin2 myelofibrosis; KER-047 Clin2 iron deficiency anemia, Clin1 iron deficiency anemia in MDS & MF; KER-012 Clin1PAH; undisclosed Clin0 musculoskeletal conditions

About:

Keros Therapeutics is discovering and developing treatments for rare hematologic and musculoskeletal disorders. A wide range of disorders are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-β). At Keros, they are using their protein engineering and drug development expertise to uncover targets within the TGF-β superfamily. By developing therapeutics that can intervene in this pathway, Keros aims to target pathways critical for the growth, repair and maintenance of blood cells and a number of tissues including bone, skeletal muscle, adipose and heart tissue.