Herophilus

Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases

Undisclosed Clin0 Alzheimer's; 5 undisclosed programs RD Dravet syndrome, FTD, Parkinson's, 22q11.2 del syndrome, schizophrenia

Herophilus is reinventing neurological drug discovery to cure complex brain diseases. Animal models of neurological diseases have contributed to much unsuccessful research as they lack the unique aspects of human pathology. By combining complex human brain organoid models, scaled biology and machine learning, Herophilus is systematically discovering and developing novel drugs with high-confidence in clinical translatability. Machine learning is required to integrate large-scale high-dimensional phenotypic datasets and create comprehensive systems biology descriptions of brain disease. Herophilus currently has programs for Rett Syndrome, Alzheimer’s disease and Schizophrenia.