Herophilus is creating therapeutics to cure complex brain diseases. Traditional approaches to studying the brain have relied on animal models which do not recapitulate human biology and have had limited therapeutic success. Instead, Herophilus is using their complex in vitro Neuroimmune Cerebral Organoid model (NICO) to identify targets and candidate drugs. NICO combines human brain models with scaled biology and machine learning, to screen neurotherapeutic drugs with high confidence in clinical translatability. Brain models are built with patient stem cell-derived brain organoids and capture the genetic and human specific disease biology. Herophilus will use these organoids to develop a patient biobank for each disease program.
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