Harmonic Discovery

Kinome-targeting Therapies

3 additional undisclosed programs RD myelofibrosis, oncology, undisclosed

Harmonic Discovery is developing new therapeutic drugs that embrace the complexity of diseases. The current paradigm of drug discovery involves identifying drugs that target a single biological mechanism. Harmonic on the other hand are creating a new generation of therapeutics that can disrupt multiple pathways by targeting the human kinome. The kinome includes a family of 500 proteins associated with diseases such as cancer, autoimmunity and neurodegeneration. To find therapeutics, Harmonic is using their platform that integrates multiple layers of information from 3D-protein structure to systemic changes in protein gene expression using medicinal chemistry and machine learning.