Fog Pharmaceuticals

Fog Pharmaceuticals

  • Founded: 2015
  • Location: Cambridge, MA
  • Employee range: 50 - 200
  • Clinical stage: Clin1/Clin2
  • Therapy area: Oncology
  • Drug types: ONC
  • Lead product: FOG-001
  • Product link: https://fogpharma.com/pipeline/
  • Funding: $178M D Nov 2022; $107M C Mar 2021; $66M May 2018
  • Investors: ARCH Venture Partners, Milky Way Investments, Fidelity Management & Research Company, VenBio Partners, Deerfield Management, GV, Cormorant Asset Management, Invus, Farallon Capital Management, HBM Healthcare Investments, Casdin Capital, PagsGroup


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Short description:

Cell-penetrating miniproteins

Drug notes:

5 undisclosed programs RD multiple cancers

Long description:

FogPharma is developing treatments for currently undruggable disease targets. Many drugs can be classified as monoclonal antibodies that cannot access the cell interior or as small molecules that lack specificity for interior targets. FogPharma is focusing on a new class of drugs - Helicon polypeptides - that combine the targeting power of monoclonal antibodies with the cell-penetrating ability of small molecules. The polypeptides designed by FogPharma have an alpha helical shape, which confers unique drug-like properties and greater stability. FogPharma evaluates thousands of new peptides weekly in biochemical and cell-based assays to select hits to develop. FogPharma’s lead product, FOG-001, targets β-catenin, which is commonly overactive in cancer.

Jobs:

Fog Pharmaceuticals
Director, Real-World Evidence
Cambridge, MA|3 days ago
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Fog Pharmaceuticals
Senior Director, Clinical Science
Cambridge, MA|5 days ago
Fog Pharmaceuticals
Senior Compound Management Associate
Cambridge, MA|11 days ago
Fog Pharmaceuticals
Associate Director, Clinical Operations
Cambridge, MA|21 days ago
Fog Pharmaceuticals
Administrative Business Partner
Cambridge, MA|22 days ago
Fog Pharmaceuticals
Head of Toxicology
Cambridge, MA|29 days ago
Fog Pharmaceuticals
Director, Target ID and Validation
Cambridge, MA|43 days ago
Fog Pharmaceuticals
Principal / Senior Scientist, Process Chemistry
Cambridge, MA|86 days ago
FogPharma
AD / Director, Machine Learning
Cambridge, MA|100+ days ago


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