Federation Bio

Federation Bio

  • Founded: 2019
  • Location: South SF, CA
  • Employee range: 11 - 50
  • Clinical stage: Clin1
  • Therapy area: Enteric hyperoxaluria
  • Drug types: NPH, GI, ONC
  • Lead product: FB-001
  • Product link: https://www.federation.bio/pipeline/
  • Funding: $50M Oct 2020



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Short description:

Design, discover, and develop robust communities of microbes

Drug notes:

FB-003 Clin0 IBD; undisclosed RD oncology; undisclosed programs RD/Clin0 undisclosed

Long description:

Federation Bio is developing microbiome-based therapeutics to combat and reverse serious diseases. Both the gut and skin microbiome has now been linked with human conditions such as eczema, metabolic disorders and Parkinson’s disease. Federation is using this insight to engineer single-strain live biotherapeutic products to manipulate the immune and metabolic systems in disease. In addition, Federation is using a separate platform to transplant massive synthetic microbial consortia, essentially creating a full-scale gut community from scratch. Federation’s lead program is for secondary hyperoxaluria where they aim to transplant gut microbes to break down the oxalate and reduce kidney stone formation.


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