Edgewise Therapeutics

Edgewise Therapeutics

  • Founded: 2017
  • Location: Boulder, CO
  • Employee range: 11 - 50
  • Clinical stage: Clin2
  • Therapy area: Becker muscular dystrophy
  • Drug types: GEN, MUS, CVV, PED
  • Lead product: EDG-5506
  • Product link: https://edgewisetx.com/science/211
  • Funding: $138M stock Sep 2022; $202M IPO Mar 2021; $50M B Sep 2019


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Short description:

Small Molecules for Musculoskeletal Diseases

Drug notes:

Also Clin2 DMD, Clin1 limb-girdle muscular dystrophy, McArdle disease; EDG-7500 Clin0 hypertrophic cardiomyopathy; EDG-003 Clin0 cardiovascular condition

Long description:

Edgewise Therapeutics is developing precision medicines to treat rare muscle disorders. Patients with Duchenne (DMD) or Becker (BMD) muscular dystrophy new muscle fiber formation cannot keep up with fiber collapse resulting in loss of muscle function. Using an integrated knowledge of muscle physiology at a whole-body level, Edgewise is discovering innovative solutions that directly target the muscle fibers of patients with rare muscle disorders. Powered by their proprietary drug discovery platform, Edgewise is designing their drugs to reduce muscle stress in fast skeletal muscle fibers which are more prone to injury in DMD and BMD patients. For example, Edgewise’s lead candidate, EDG-5506, selectively targets the motor protein myosin to reduce stress and is now in Phase 2 clinical trials.

Jobs:

Edgewise Therapeutics
Director/Sr Director, Data Management
Colorado, United States|5 days ago
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Edgewise Therapeutics
Clinical Scientist – Musculoskeletal
European Union|21 days ago
Edgewise Therapeutics
Medical Director/Clinical Development Physician – ...
United States|21 days ago
Edgewise Therapeutics
Manager/Sr. Manager/Associate Director, Clinical O...
Boulder, CO|29 days ago
Edgewise Therapeutics
Medical Director/Clinical Development Physician – ...
Massachusetts, United States|41 days ago
Edgewise Therapeutics
Clinical Scientist – Musculoskeletal (based in UK/...
United Kingdom|43 days ago
Edgewise Therapeutics
Vice President, Cardiovascular Clinical Developmen...
Colorado, Stati Uniti d'America|63 days ago
Edgewise Therapeutics
Manager/Senior Manager/Associate Director, Regulat...
Colorado, United States|71 days ago


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