Dyne Therapeutics

Dyne Therapeutics

Founded: 2017

Location: Waltham, MA

Employee range: 1 - 10

Clinical stage: Clin1/Clin2

Therapy area: Myotonic muscular dystrophy type 1

Drug types: MUS, GEN

Lead product: DYNE-101

Funding: $168M stock Jan 2021; $268M IPO Sep 2020; $115M Aug 2020; $50M Apr 2019

Investors: Vida Ventures, Surveyor Capital, Wellington Management Company, Logos Capital, Franklin Templeton, Atlas Venture, Forbion, MPM Capital

Business:

Antibody-Oligonucleotide Treatments for Muscle Diseases

Drug notes:

DYNE-251 Clin1/Clin2 DMD; DYNE-301 Clin0 facioscapulohumeral muscular dystrophy; 4 undisclosed programs RD/Clin0 DMD

About:

Dyne Therapeutics is developing therapeutics for patients living with muscle diseases with the aim of stopping or reversing disease progression. Many muscular diseases have a genetic underpinning: Dyne is using their proprietary FORCETM platform to develop targeted, modern oligonucleotide therapeutics to address these genetic defects and slow disease progression. Dyne’s therapeutics consist of an antibody to target the drug to the muscle, a payload that consists of either antisense oligonucleotides or short interfering RNAs to target the genetic basis of the disease, and linker to combine the two units. Dyne’s lead product candidate, DYNE-101 is currently anticipated for clinical trials for patients with Myotonic Dystrophy.

VP, Technical Development

Waltham, MA|1 day ago

Associate Director, Medical Science Liaison - Nort...

Remote|1 day ago

Director, Medical Science Liaison - Northeast, Sou...

Waltham, MA|1 day ago

Senior Manager, Analytical Development and Quality...

Waltham, MA|1 day ago

Director, Supply Chain Planning

Waltham, MA|5 days ago

Director, Small Molecule CMC

Waltham, MA|12 days ago

Research Associate, Neuromuscular Research

Waltham, MA|13 days ago

Director, Drug Safety & Pharmacovigilance Scientis...

Waltham, MA|13 days ago

Clinical Trial Associate

Waltham, MA|13 days ago

SVP, Head of Pharmacovigilance

Waltham, MA|13 days ago

Executive Assistant to the G&A Executives

Waltham, MA|21 days ago

Vice President, Talent Acquisition

Waltham, MA|22 days ago

Director, Clinical Supply

Waltham, MA|27 days ago

Senior Director, Drug Safety and Pharmacovigilance...

Waltham, MA|35 days ago

Senior Director, Senior Corporate Counsel

Waltham, MA|40 days ago

Executive Director, Medical Affairs Managed Market...

Waltham, MA|47 days ago

Senior Director, Regulatory Affairs

Waltham, MA|47 days ago

Associate Director, Clinical Scientist

Waltham, MA|54 days ago

Executive Director, Clinical Development

Waltham, MA|54 days ago

Director, Program Management

Waltham, MA|54 days ago

Senior Director, Clinical Development

Waltham, MA|54 days ago

Associate Director, Medical Science Liaison

Waltham, MA|55 days ago

Contracts Manager

Waltham, MA|63 days ago

Principal Scientist, Protein Engineering

Waltham, MA|67 days ago

Director, Medical Science Liaison

Waltham, MA|67 days ago

Manager, Quality Control

Waltham, MA|68 days ago

Animal Care Associate

Waltham, MA|68 days ago

Senior Director, Global Health Economics & Outcome...

Waltham, MA|74 days ago

Associate Director, Regulatory Affairs

Waltham, MA|85 days ago

Senior Manager, Clinical Supply

Waltham, MA|100+ days ago

Associate Director, Clinical Operations Study Lead...

Waltham, MA|100+ days ago

Associate Director, Statistical Programming

Waltham, MA|100+ days ago

Associate Director, Biostatistics

Waltham, MA|100+ days ago

Associate Director, Quantitative Pharmacology

Waltham, MA|100+ days ago

Director, Clinical Pharmacology and Pharmacometric...

Waltham, MA|100+ days ago

VP, Program Team Leader

Waltham, MA|100+ days ago

SVP, US Medical Affairs Lead

Waltham, MA|100+ days ago

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