Dyne Therapeutics

Dyne Therapeutics

  • Founded: 2017
  • Location: Waltham, MA
  • Employee range: 1 - 10
  • Clinical stage: Clin1/Clin2
  • Therapy area: Myotonic muscular dystrophy type 1
  • Drug types: MUS, GEN
  • Lead product: DYNE-101
  • Product link: https://www.dyne-tx.com/pipeline/
  • Funding: $168M stock Jan 2021; $268M IPO Sep 2020; $115M Aug 2020; $50M Apr 2019
  • Investors: Vida Ventures, Surveyor Capital, Wellington Management Company, Logos Capital, Franklin Templeton, Atlas Venture, Forbion, MPM Capital


dyne-tx.com

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Short description:

Antibody-Oligonucleotide Treatments for Muscle Diseases

Drug notes:

DYNE-251 Clin1/Clin2 DMD; DYNE-301 Clin0 facioscapulohumeral muscular dystrophy; 4 undisclosed programs RD/Clin0 DMD

Long description:

Dyne Therapeutics is developing therapeutics for patients living with muscle diseases with the aim of stopping or reversing disease progression. Many muscular diseases have a genetic underpinning: Dyne is using their proprietary FORCETM platform to develop targeted, modern oligonucleotide therapeutics to address these genetic defects and slow disease progression. Dyne’s therapeutics consist of an antibody to target the drug to the muscle, a payload that consists of either antisense oligonucleotides or short interfering RNAs to target the genetic basis of the disease, and linker to combine the two units. Dyne’s lead product candidate, DYNE-101 is currently anticipated for clinical trials for patients with Myotonic Dystrophy.

Jobs:

Dyne Therapeutics
Principal Scientist, Bioinformatics Data Science
Waltham, MA|4 days ago
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Dyne Therapeutics
Associate Director, Scientific and Medical Communi...
Waltham, MA|5 days ago
Dyne Therapeutics
Scientist, Analytical Development & Quality Contro...
Waltham, MA|30 days ago
Dyne Therapeutics
Scientist, Neuromuscular Research
Waltham, MA|31 days ago
Dyne Therapeutics
Clinical Project Manager
Waltham, MA|40 days ago
Dyne Therapeutics
Senior Manager, TMF and Inspection Readiness
Waltham, MA|41 days ago
Dyne Therapeutics
Executive Director, U.S. Medical Science Liaison
Waltham, MA|47 days ago
Dyne Therapeutics
Scientist, Platform
Waltham, MA|52 days ago
Dyne Therapeutics
VP, Head of Program Management
Waltham, MA|53 days ago
Dyne Therapeutics
Associate Director, Clinical Operations Study Lead...
Waltham, MA|67 days ago
Dyne Therapeutics
Senior Director, Clinical Operations Program Lead ...
Waltham, MA|67 days ago
Dyne Therapeutics
Associate Director, Clinical Data Analyst
Waltham, MA|67 days ago
Dyne Therapeutics
SVP, Head of Data Analytics
Waltham, MA|96 days ago
Dyne Therapeutics
Associate Director, Clinical Scientist
Waltham, MA|100+ days ago
Dyne Therapeutics
VP, Global Market Access
Waltham, MA|100+ days ago
Dyne Therapeutics
Associate Director, Statistical Programming
Waltham, MA|100+ days ago
Dyne Therapeutics
Senior Scientist, Bioanalysis
Waltham, MA|100+ days ago
Dyne Therapeutics
Executive Director, Medical Director
Waltham, MA|100+ days ago
Dyne Therapeutics
SVP, Head of Clinical Development
Waltham, MA|100+ days ago
Dyne Therapeutics
Director, CMC Bioconjugation & External Manufactur...
Waltham, MA|100+ days ago
Dyne Therapeutics
Senior Director, Drug Safety and Pharmacovigilance...
Waltham, MA|100+ days ago
Dyne Therapeutics
Director, Regulatory Affairs
Waltham, MA|100+ days ago
Dyne Therapeutics
Senior Director, Clinical Pharmacology
Waltham, MA|100+ days ago


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