Dianthus Therapeutics

Dianthus Therapeutics

  • Founded: 2019
  • Location: Waltham, MA
  • Employee range: 1 - 10
  • Clinical stage: Clin1
  • Therapy area: Autoimmune diseases
  • Drug types: IMM, RAR
  • Lead product: DNTH103
  • Product link: https://dianthustx.com/?pag=1&category=3
  • Funding: $100M A Apr 2022
  • Investors: 5AM Ventures, Avidity Partners, Fidelity Management & Research Company, Wedbush Healthcare Partners, Fairmount, Tellus BioVentures, Venrock Healthcare Capital Partners


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Short description:

Monoclonal Antibodies

Drug notes:

DNTH200 RD undisclosed; DNTH300 RD undisclosed

Long description:

Dianthus Therapeutics is developing novel Complement therapeutics to improve the quality of life of patients with autoimmune diseases. The Complement system is part of the innate immune response that can get activated in autoimmune diseases. Dianthus is designing selective monoclonal antibodies that target components of the Complement system to reduce their activity. The antibodies are modified to have a longer half-life, thus enabling therapeutics reduced dose levels and frequency. Dianthus’ pipeline is in preclinical stages, with the most advanced, DNTH103, targeting active Complement C1s. DNTH103 is selective for the active, not inactive, C1s which sets it apart from current antibody therapies and could offer a more convenient subcutaneous therapy for patients.

Jobs:

Dianthus Therapeutics
Director, Clinical Operations
Remote|9 days ago
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Dianthus Therapeutics
Director, SEC Reporting and Technical Accounting
Remote|9 days ago
Dianthus Therapeutics
Senior Manager, Data Sciences
Remote|9 days ago
Dianthus Therapeutics
Senior Bioanalytical Scientist
Waltham, MA|32 days ago
Dianthus Therapeutics
Director, Immunology
Waltham, MA|40 days ago
Dianthus Therapeutics
Senior Director, Global Drug Safety
Remote|80 days ago
Dianthus Therapeutics
Senior Director, Medical Writing
Remote|100+ days ago


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