Chimeron Bio

Chimeron Bio

  • Founded: 2015
  • Location: Philadelphia, PA
  • Employee range: 1 - 10
  • Clinical stage: RD
  • Therapy area: Oncology
  • Drug types: ONC, INF, VAC, RAR, GEN
  • Lead product: ChaESAR platform
  • Product link:
  • Funding: <10M

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Short description:

Cancer Immunotherapy

Drug notes:

Also RD infectious diseases, rare genetic diseases

Long description:

Chimeron Bio is developing personalized gene therapies using self-amplifying RNAs (saRNA). saRNAs are a recent advancement in synthetic genomics that has the potential to transform RNA therapy. Chimeron has developed a novel nanoparticle technology called Chimera Encased saRNA (ChaESAR) that harnesses the properties of saRNAs and synthetic genomics to engineer novel RNA drugs. Chimeron’s ChaESAR platform leverages the chimera encased saRNA to achieve superior expression and broader dynamics range compared to current mRNA technologies. Chimeron’s current pipeline includes programs in oncology, liver and vaccines for infectious diseases.


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