CAR-Natural Killer Cell Therapies
CAT-248 RD renal cell carcinoma; undisclosed RD solid tumors
Catamaran Bio is developing off-the-shelf chimeric antigen receptor (CAR) natural killer (NK) cell therapies to address a broad range of cancers. NK cells are critical components of the immune system that possess natural cancer-fighting properties. Catamaran is using synthetic biology and non-viral cell engineering to create novel CAR-NK cells that are capable of treating solid tumors by combining new functional attributes with their inherent cancer-killing properties. To achieve this, Catamaran developed TAILWIND®, their proprietary suite of technologies that CAR-NK cell therapy development and manufacturing for multiple cancer types. Catamaran’s lead candidate, CAT-248, has been engineered with four functional modifications and will be tested in clinical studies for renal cell carcinoma.