Caraway Therapeutics

Caraway Therapeutics

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  • Founded: 2018
  • Location: Cambridge, MA
  • Employee range: 11 - 50
  • Clinical stage: Clin0
  • Therapy area: Non CNS rare disease
  • Drug types: NEU, RAR
  • Lead product: TRPML1
  • Funding: $23M A Nov 2018
  • Investors: MRLV, AbbVie Ventures, Amgen Ventures, Alexandria Venture Investments, Mayo Clinic, SV Health Investors, Dementia Discovery Fund 


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Drug notes:

Also Clin0 GBA-Parkinson's; TMEM175 Clin0 Parkinson's; undisclosed RD undisclosed

About:

Caraway Therapeutics is inventing novel treatments for neurodegenerative diseases by modulating the lysosome. The lysosome is the cell’s recycling center that clears toxic materials and defective cellular components. Mutations that impair this process are associated with multiple neurodegenerative diseases. Caraway’s integrated drug discovery platform combines patient genomic data and patient-derived induced pluripotent stem cells to screen and identify small molecule therapeutics that can boost cellular clearance to restore balance to those with the disease. In addition, the platform incorporates high content imaging and electrophysiology. Caraway’s pipeline is currently at preclinicals stages.

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