Calico
Edit info- Founded: 2014
- Location: South SF, CA
- Employee range: 200 - 500
- Clinical stage: Clin1b
- Therapy area: Vanishing white matter disease
- Drug types: GER, ONC, NEU
- Lead product: ABBV-CLS-7262 (partner AbbVie)
- Funding: not disclosed
calicolabs.com linkedin.com job board
Business:
Aging treatments
Drug notes:
Also Clin1 ALS; ABBV-CLS-579 Clin1 solid tumors (partner: AbbVie); ABBV-CLS-484 Clin1 solid tumors (partner: AbbVie), undisclosed programs RD/Clin0 oncology, neurological diseases, tissue homeostasis & repair
About:
Calico Life Sciences is investigating the basic biology of aging using state-of-the-art technology and advanced computation. Unlike traditional biotechnology companies, Calico focuses on biology first with its wide range of equipment and facilities and uses that information to develop interventions that enable people to live longer and healthier lives. For example, Calico works with different model organisms such as yeast, worms, mice and naked mole rats. The long-term aim of Calico is to identify new targets, not being pursued by others, for diseases commonly associated with aging. Calico’s portfolio currently includes more than 20 early- and late-stage preclinical compounds in cancer, neurological diseases and tissue homeostasis and repair.
Jobs:
Intern, Applied Machine Learning for Genomic Rearr...
South San Francisco, CA|19 days ago
Intern, Cell Biology - Cell cycle-dependent lysoso...
South San Francisco, CA|19 days ago
Intern, Data Engineering - EDA / ML Infrastructure...
South San Francisco, CA|19 days ago
Intern, Immune Aging (BS/MS)
South San Francisco, CA|19 days ago
Intern, Lab Automation (BS)
South San Francisco, CA|19 days ago
Intern, Machine Learning - Spatial Profiling (MS/P...
South San Francisco, CA|19 days ago
Intern, Neuroimmunology (BS)
South San Francisco, CA|19 days ago
Intern, Systems Biology of MSC Differentiation (BS...
South San Francisco, CA|19 days ago
Intern, Machine Learning - Protein Design (MS/PhD)...
South San Francisco, CA|20 days ago
Intern, Genetic Perturbation (BS)
South San Francisco, CA|25 days ago
Associate Director, Drug Development, Outsourcing ...
South San Francisco, CA|31 days ago
Associate Director, Medical/Safety Science
South San Francisco, CA|33 days ago
Associate Director/Director, Clinical Pharmacology...
South San Francisco, CA|39 days ago
Head of CMC
South San Francisco, CA|39 days ago
Principal Scientist/Associate Director, DMPK
South San Francisco, CA|39 days ago
Director/Senior Director, Antibody Discovery and E...
South San Francisco, CA|60 days ago
Senior Research Associate, Cell Biology and Bioche...
South San Francisco, CA|61 days ago
Senior Research Associate, Protein Sciences
South San Francisco, CA|61 days ago
Scientist, Aging Metabolism
South San Francisco, CA|75 days ago
Principal Scientist, Molecular Biology, Biochemist...
South San Francisco, CA|75 days ago
Scientist, Immunology, Genetics, and Vascular Dise...
South San Francisco, CA|75 days ago
Scientist, Cancer Metabolism
South San Francisco, CA|75 days ago
Senior / Staff Machine Learning Infrastructure Eng...
South San Francisco, CA|79 days ago
Senior Director, Contracts, Alliances and Intellec...
South San Francisco, CA|82 days ago
Senior Scientist, Translational Medicine
South San Francisco, CA|86 days ago
Senior Software Engineer, Laboratory Automation
South San Francisco, CA|88 days ago
Machine Learning Research Scientist / Senior Machi...
South San Francisco, CA|97 days ago
Scientist, Spatial Genomics
South San Francisco, CA|100+ days ago
Senior Machine Learning Engineer
South San Francisco, CA|100+ days ago
Senior Data Scientist, Biological Discovery
South San Francisco, CA|100+ days ago
Scientist, Immune Aging
South San Francisco, CA|100+ days ago
Scientist, Proteomics
South San Francisco, CA|100+ days ago
Associate Director/Director, Business Development
South San Francisco, CA|100+ days ago
Senior Scientist/Principal Scientist, Biochemist a...
South San Francisco, CA|100+ days ago
Computational Biologist, Epidemiology
South San Francisco, CA|100+ days ago
Machine Learning Engineer
South San Francisco, CA|100+ days ago
Medical Director, Clinical Oncology
South San Francisco, CA|100+ days ago
Head of Human Biology
South San Francisco, CA|100+ days ago
Principal Investigator, Vascular System Homeostasi...
South San Francisco, CA|100+ days ago
News:
Rare male calico cat born in the Golden Isles - Brunswick News
googlenews
Dec 9, 2024
Science/business updates
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Calico Ghost Town hosts spooky weddings on Halloween Day - San Bernardino County (.gov)
googlenews
Nov 7, 2024
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Google’s AI attempts to predict how yeast cell genes will express themselves
crunchbase
Apr 29, 2020
Science/business updates
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Data libraries: the missing element for modeling biological systems
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Jan 2, 2025
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CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1
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Jan 2, 2025
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Age and diet shape the genetic architecture of body weight in diversity outbred mice
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Jan 2, 2025
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Development of an α-Klotho Recognizing High-Affinity Peptide Probe from In-Solution Enrichment
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Jan 2, 2025
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Tigera Unveils Calico Container Networking Interface for Azure Kubernetes Service
crunchbase
Apr 25, 2022
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Google’s life-prolonging moonshot Calico partners with C4 Therapeutics
crunchbase
Mar 24, 2017
Science/business updates
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Anti-Aging Startup Raises $116 Million With Bezos Backing
crunchbase
Oct 27, 2016
Funding-related
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Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity
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Jan 2, 2025
Science/business updates
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An immune-based tool platform for in vivo cell clearance
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Jan 2, 2025
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Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning
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Jan 2, 2025
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eIF2B activator prevents neurological defects caused by a chronic integrated stress response
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Jan 2, 2025
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Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning
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Jan 2, 2025
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Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population
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Jan 2, 2025
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An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
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Jan 2, 2025
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Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time
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Jan 2, 2025
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A molecular cell atlas of the human lung from single-cell RNA sequencing
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Jan 2, 2025
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Calico Appoints Michael Lenardo, M.D., as Chief Scientific Officer - PR Newswire
googlenews
Mar 28, 2024
New hires
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Some Exciting Future Directions for Work on Naked Mole-Rats
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Jan 2, 2025
Science/business updates
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Danger-Klipper Fork Renamed To Kalico - Hackaday
googlenews
Dec 11, 2024
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Real-time multi-angle projection imaging of biological dynamics
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Jan 2, 2025
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Calico brings on Amgen's translational R&D head to lead ...
fiercebiotech.com
Dec 27, 2024
New hires
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Mom Trains Her Calico Cat to Respond to Gloria Estefan and It's Like a Nonstop Party - Parade Pets
googlenews
Nov 17, 2024
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Evolution of T cells in the cancer-resistant naked mole-rat
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Jan 2, 2025
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PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice
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Jan 2, 2025
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High-Throughput Proteome Profiling of Plasma and Native Plasma Complexes Using Native Chromatography
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Jan 2, 2025
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Morehead City leaders working to get Calico Bay Park project going - WNCT
googlenews
Dec 9, 2024
Funding-related
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The Exploration of Novel Regulatory Relationships Drives Haloarchaeal Operon-Like Structural Dynamics over Short Evolutionary Distances
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Jan 2, 2025
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Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice
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Jan 2, 2025
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Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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Jan 2, 2025
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Editorial: Effects of vascular function and aging on brain circulation and neurodegeneration
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Jan 2, 2025
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Google's Calico snags access to Ancestry.com data to find ...
fiercebiotech.com
Dec 27, 2024
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Liver shape analysis using statistical parametric maps at population scale
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Jan 2, 2025
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Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
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Jan 2, 2025
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A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage
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Jan 2, 2025
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Calico makes another big hire in quest to unlock healthy aging
crunchbase
Aug 18, 2016
New hires
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Pfizer hires Settleman from Calico to lead cancer R&D
fiercebiotech.com
Dec 27, 2024
New hires
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Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I
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Jan 2, 2025
Science/business updates
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Calico Hair Color: Best Calico Hairstyle Ideas 2025 - Perfect Corp.
googlenews
Dec 6, 2024
Science/business updates
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AbbVie and Calico renew their aging research ...
fiercebiotech.com
Dec 27, 2024
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Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study
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Jan 2, 2025
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Precision MRI phenotyping enables detection of small changes in body composition for longitudinal cohorts
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Jan 2, 2025
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Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells
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Jan 2, 2025
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Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
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Jan 2, 2025
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Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
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Jan 2, 2025
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Spontaneous Disease and Pathology of Naked Mole-Rats
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Jan 2, 2025
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Google's stealthy Calico inks an R&D deal for new ...
fiercebiotech.com
Dec 27, 2024
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Precision MRI phenotyping of muscle volume and quality at a population scale
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Jan 2, 2025
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Explore Life at Calico: Our Regulatory Affairs team bridges science and governance to help Calico introduce new medical treatment options that may help alleviate age-related diseases and fulfill high
linkedin
Oct 27, 2024
New hires
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Why Calico Critters Are the Ultimate Summer Inspiration - Thrillist
googlenews
Aug 9, 2024
Science/business updates
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Rafay Deploys Calico Open Source to Achieve Turnkey Kubernetes Security on AWS
crunchbase
Jan 23, 2024
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“Calico Hair” Is The Cat-Inspired Trend Taking Over BeautyTok - Bustle
googlenews
Oct 14, 2024
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Differentiation reveals latent features of aging and an energy barrier in murine myogenesis
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Jan 2, 2025
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Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs
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Jan 2, 2025
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Sugar phosphate activation of the stress sensor eIF2B
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Jan 2, 2025
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Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
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Jan 2, 2025
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Quilts and Cats of Calico review for PC, Nintendo Switch - Gaming Age
googlenews
Apr 15, 2024
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Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis
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Jan 2, 2025
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S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy
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Jan 2, 2025
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Google Is Scouring Ancestry.com to Find Out What's in Your Genes
crunchbase
Jul 21, 2015
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Live Long(er) And Prosper: A Look At Top VC Investments In Radical Life Extension
crunchbase
Jul 9, 2021
Funding-related
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LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice
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Jan 2, 2025
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Genetic interaction profiles of regulatory kinases differ between environmental conditions and cellular states
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Jan 2, 2025
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Five years later, with double the demographic data, naked mole-rat mortality rates continue to defy Gompertzian laws by not increasing with age
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Jan 2, 2025
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Learning causal networks using inducible transcription factors and transcriptome‐wide time series
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Jan 2, 2025
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GOT1 regulates CD8+ effector and memory T cell generation
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Jan 2, 2025
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Calico Cat Obsessed With Teasing Toller Sibling Is Such a Mood - PetHelpful
googlenews
Jul 11, 2024
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Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases
web
Jan 2, 2025
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Joint inference of physiological network and survival analysis identifies factors associated with aging rate
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Jan 2, 2025
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Independent regulation of age associated fat accumulation and longevity
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Jan 2, 2025
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Reversibly Reactive Affinity Selection–Mass Spectrometry Enables Identification of Covalent Peptide Binders
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Jan 2, 2025
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Insights into the Molecular Basis of Genome Stability and Pristine Proteostasis in Naked Mole-Rats
web
Jan 2, 2025
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A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics
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Jan 2, 2025
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Electrophile Scanning Reveals Reactivity Hotspots for the Design of Covalent Peptide Binders
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Jan 2, 2025
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It's #PostdocAppreciationWeek, and we're proud to highlight the impactful work of some of our postdoctoral fellows who help drive scientific discovery at Calico.
Thula Yoganathan is a postdoc whose r
linkedin
Sep 27, 2024
Science/business updates
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Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging
web
Jan 2, 2025
Science/business updates
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A Visual Framework for Classifying Determinants of Cell Size
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Jan 2, 2025
Science/business updates
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Calico loses its second executive in 4 months as Daphne ...
fiercebiotech.com
Dec 27, 2024
New hires
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Calico Appoints Michael Lenardo, M.D., as Chief Scientific Officer
crunchbase
Mar 28, 2024
New hires
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NetSuite and the Year of the Vertical Cloud
crunchbase
May 23, 2016
Science/business updates
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Are mitochondria the main contributor of reactive oxygen species in cells?
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Jan 2, 2025
Science/business updates
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A data analysis framework for combining multiple batches increases the power of isobaric proteomics experiments
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Jan 2, 2025
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Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis
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Jan 2, 2025
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Ginger, tortie, calico – the mystery gene responsible for orange colour in cat coats has been found - The Conversation
googlenews
Dec 3, 2024
Science/business updates
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Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response
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Jan 2, 2025
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Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6
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Jan 2, 2025
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Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis
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Jan 2, 2025
Science/business updates
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Dissecting the anatomy of a Canadian tech seed round with Two Small Fish, Calico & Wavy
crunchbase
Dec 2, 2022
Funding-related
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scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks
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Jan 2, 2025
Science/business updates
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Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity
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Jan 2, 2025
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X projects: Alphabet's 'moonshot' ventures that could change the world
crunchbase
Feb 5, 2016
Science/business updates
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CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging
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Jan 2, 2025
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GWAS of canines identifies potential aging determinants
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Jan 2, 2025
Science/business updates
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