Cabaletta Bio

Cabaletta Bio

  • Founded: 2017
  • Location: Philadelphia, PA
  • Employee range: 11 - 50
  • Clinical stage: Clin1
  • Therapy area: Mucosal pemphigus vulgaris
  • Drug types: RAR, IMM, DRM, MUS, NEU, GEN, NPH
  • Lead product: DSG3-CAART
  • Product link: https://www.cabalettabio.com/pipeline
  • Funding: $100M stock May 2023; $75M IPO Oct 2019; $50M B Jan 2019; $38M Nov 2018


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Short description:

Chimeric Auto Antibody Receptors

Drug notes:

MuSK-CAART Clin1 myasthenia gravis; PLA2R-CAART Clin0 membranous nephropathy; CABA-201 3 efforts Clin0 SLE, undisclosed; DSG3/1-CAART RD mucocutaneous pemphigus vulgaris

Long description:

Cabaletta Bio is developing T cell therapies for patients with B cell-mediated autoimmune diseases. Engineered T cell therapy takes advantage of T cell’s natural cell-killing capabilities and redirects their specificity to disease-causing cells by inserting a gene encoding a specific receptor. Known as chimeric antigen receptor (CAR) T cells, this approach has shown much success in cancer treatment. Cabaletta is encompassing CAR T cells for Autoimmunity (CARTA) which they hope to apply to many B cell-mediated autoimmune diseases. Cabaletta’s lead candidate in preclinical stages, CABA-201, is a fully human CD19 CARTA approach which has the potential to eliminate disease-causing B cells and allow for healthy B cell repopulation.

Jobs:

Cabaletta Bio
Senior Scientist, Process Development
Philadelphia, Pennsylvania|Not provided
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Cabaletta Bio
Senior Director Medical Affairs (Remote)
All, All|Not provided
Cabaletta Bio
Process Engineering Associate, MS&T
Philadelphia, Pennsylvania|Not provided
Cabaletta Bio
Lab Information Management (LIMS) Administrator
Philadelphia, Pennsylvania|Not provided
Cabaletta Bio
Director, Quality Assurance Operations
Philadelphia, Pennsylvania|Not provided
Cabaletta Bio
GLP Quality Control Specialist
Philadelphia, Pennsylvania|Not provided
Cabaletta Bio
QA & Compliance LMS Training Specialist
Philadelphia, Pennsylvania|Not provided
Cabaletta Bio
Senior Director, Process Development
Philadelphia, Pennsylvania|Not provided
Cabaletta Bio
Associate Director/Director, Clinical Data Managem...
All, All|Not provided


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