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Axsome Therapeutics

Axsome Therapeutics

Founded: 2012

Location: New York, NY

Employee range: 50 - 200

Clinical stage: COM

Therapy area: Excessive daytime sleepiness due to sleep apnea or narcolepsy

Drug types: PSY, NEU, PN, ABU, ZZZ

Lead product: Sunosi

Product link: https://www.axsome.com/axs-portfolio/pipeline

Funding: $225M stock Jun 2023; $23.3M stock Jan 2019

Short description:

CNS treatments

Drug notes:

Auvelity COM depression; AXS-07 NDA migraine; AXS-14 Clin3 fibromyalgia; AXS-05 Clin3 Alzheimer's agitation, Clin2 smoking cessation; AXS-12 Clin3 cataplexy in narcolepsy (ODD); solriamfetol Clin2 ADHD

Long description:

Axsome Therapeutics is developing therapies that target the central nervous system (CNS) to help patients with depression, migraines, narcolepsy, fibromyalgia and smoking addiction. Axsome is designing therapeutic options with novel mechanisms of action to transform the current approach to treat CNS disorders. This approach involves internally-derived candidates and in-licensed candidates with development and commercialization. Axsome’s pipeline is already diversified with 4 lead compounds in Phase 1,2 & 3 clinical trials targeting conditions that currently have limited treatment options. One compound, AXS-05, is an oral NMDA receptor antagonist to treat depression and Alzheimer’s disease agitation.

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