Axial Therapeutics

Axial Therapeutics

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  • Founded: 2016
  • Location: Woburn, MA
  • Employee range: 11 - 50
  • Clinical stage: Clin2
  • Therapy area: Autism irritability
  • Drug types: NEU, PSY, ONC
  • Lead product: AB-2004
  • Funding: $37.25M C Oct 2021; $25M B Feb 2019; $19M A Nov 2016
  • Investors: Seventure Partners, Longwood Fund, Domain Associates, Heritage Medical Systems, rich people in SoCal


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Drug notes:

AB-2004-PTR Clin0 autism irritability; AB-5006 Clin0 Parkinson's; AB-6000 2 efforts Clin0 oncology

About:

Axial Therapeutics focuses on developing novel treatments for neurological diseases and disorders through the gut microbiome. They hope to improve the lives of patients with autism spectrum disorders and Parkinson’s disease through their microbial inspired therapeutics. Their science is based off research by co-founder Dr. Sarkis Mazmanian, who has done ground-breaking work, establishing key concepts surrounding the role of the gut-brain axis in neurodevelopmental disorders and neurodegenerative diseases. Axial Therapeutics’ platform is identifying new therapeutic targets and providing small molecule therapies that target the gut with minimal systemic absorption.

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