Ambagon Therapeutics

Ambagon Therapeutics

    Company info:

  • 1-50
  • 2020
  • San Francisco, CA
  • 100-500M

Claim company profile

About company:

Ambagon Therapeutics is enhancing the activity of tumor suppressors by creating cancer molecule therapeutics. 14-3-3 proteins are adaptor proteins that play a key role in a large number of disease-related pathways, but are intrinsically disordered, making it hard to design small molecule binders. However, these disordered regions become ordered when 14-3-3 binds other “client” protein interactors. Different clients create structurally unique pockets on 14-3-3 enabling Ambagon to develop small molecules that can stabilize specific 14-3–3:client interactions. Ambagon has built an extensive database of 14-3-3:client protein structures to quickly identify the most promising candidates for screening. Amabagon now has five programs in early discovery and expects one to reach development by 2023.


Ambagon Therapeutics
All jobs
See jobs

Claim company profile to post jobs directly on this page and this website.

© 2023 Work In Biotech LLC
Personal data

Terms of Service

Privacy Policy