AltPep is developing treatments and detection tools for amyloid diseases. Unfolded or misfolded proteins can accumulate into harmful deposits that have been linked with neurodegenerative and systemic disorders called amyloid diseases. AltPep identified a novel protein structure, alpha-sheet, using computer modeling techniques that is thought to be causal to misfolded aggregates in over 50 amyloid diseases. Using this knowledge, AltPep has created a platform of de novo synthetic peptides designed to target and neutralize the impact of these misfolded aggregates at the early stages of disease. In addition, AltPep is using the presence of these aggregates to create their SOBA Diagnostic platform that is being investigated for use in Alzheimer’s and Parkinson’s diseases.

<p>AltPep is developing treatments and detection tools for amyloid diseases. Unfolded or misfolded proteins can accumulate into harmful deposits that have been linked with neurodegenerative and systemic disorders called amyloid diseases. AltPep identified a novel protein structure, alpha-sheet, using computer modeling techniques that is thought to be causal to misfolded aggregates in over 50 amyloid diseases. Using this knowledge, AltPep has created a platform of de novo synthetic peptides designed to target and neutralize the impact of these misfolded aggregates at the early stages of disease. In addition, AltPep is using the presence of these aggregates to create their SOBA Diagnostic platform that is being investigated for use in Alzheimer’s and Parkinson’s diseases.</p>


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