Admera Health is designing advanced molecular diagnostics and pharmacogenomics (PGx) solutions to facilitate personalized medicine and non-invasive cancer testing. PGx involves understanding the relationship between a person's genetic makeup and their response to different drugs to develop effective and safe medications tailored to the individual. Admera has built their flagship product, PGxOne Plus, that incorporates next-generation gene sequencing design applications and expert data curation to offer a comprehensive test built to enable smarter and safer medication management. Admera’s portfolio of genetic tests also include OncoGxOne for solid tumor profiling and CardioGxOne for cardiovascular disease conditions.

<p>Admera Health is designing advanced molecular diagnostics and pharmacogenomics (PGx) solutions to facilitate personalized medicine and non-invasive cancer testing. PGx involves understanding the relationship between a person&#39;s genetic makeup and their response to different drugs to develop effective and safe medications tailored to the individual. Admera has built their flagship product, PGxOne Plus, that incorporates next-generation gene sequencing design applications and expert data curation to offer a comprehensive test built to enable smarter and safer medication management. Admera’s portfolio of genetic tests also include OncoGxOne for solid tumor profiling and CardioGxOne for cardiovascular disease conditions.</p>


Admera Health

Sales Executive/Senior Sales Executive  (NGS Services, Great Lakes Territory)

The neotypification of Frontonia vernalis (Ehrenberg, 1833) Ehrenberg, 1838 and the description of Frontonia paravernalis sp. nov. trigger a critical revision of frontoniid systematics

Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM. A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer. Cancer Discov. 2021 Jul;11(7):1754-1773. doi: 10.1158/2159-8290.CD-20-1325. Epub 2021 Feb 19. PMID: 33608386; PMCID: PMC8292166.

Myung Chang Lee, Hongchen Cai, Christopher W. Murray, Chuan Li, Yan Ting Shue, Laura Andrejka, Andy L. He, Alessandra M.E. Holzem, Alexandros P. Drainas, Julie H. Ko, Garry L. Coles, Christina Kong, Shirley Zhu, ChunFang Zhu, Jason Wang, Matt van de Rijn, Dmitri A. Petrov, Monte M. Winslow, Julien Sage, A multiplexed in vivo approach to identify driver genes in small cell lung cancer,Cell Reports,Volume 42, Issue 1,2023,111990,ISSN 2211-1247,https://doi.org/10.1016/j.celrep.2023.111990.

Singleron Biotechnologies

Connecting structure to function with the recovery of over 1000 high-quality metagenome-assembled genomes from activated sludge using long-read sequencing

Risk Factors for Antimicrobial Resistance in Turkey Farms: A Cross-Sectional Study in Three European Countries

Bradley CP, Chen C, Oetjen KA, Yan C, Panjwani R, Hauffe S, Calvo KR, Yuan C, Patel PA, Montgomery ND, Foster MC, Battiwalla M, Barrett AJ, Gibbons RJ, Ito S. Persistence of skewed X-chromosome inactivation in pre-B acute lymphoblastic leukemia of a female ATRX mutation carrier. Blood Adv. 2019 Sep 10;3(17):2627-2631. doi: 10.1182/bloodadvances.2019000013. PMID: 31501157; PMCID: PMC6737413.

Dysbiosis in marine aquaculture revealed through microbiome analysis: reverse ecology for environmental sustainability

 AdMoER launches Beta testing of contagion-tracking app 

Daring to be differential: metabarcoding analysis of soil and plant-related microbial communities using amplicon sequence variants and operational taxonomical units


  
    Admera Health Introduces a New Clinical-Grade Whole Genome Sequencing Solution to Its Suite of Genomic Services
  

Bosco DB, Zheng J, Xu Z, Peng J, Eyo UB, Tang K, Yan C, Huang J, Feng L, Wu G, Richardson JR, Wang H, Wu LJ. RNAseq analysis of hippocampal microglia after kainic acid-induced seizures. Mol Brain. 2018 Jun 20;11(1):34. doi: 10.1186/s13041-018-0376-5. PMID: 29925434; PMCID: PMC6011524.

Revah O, Gore F, Kelley KW, Andersen J, Sakai N, Chen X, Li MY, Birey F, Yang X, Saw NL, Baker SW, Amin ND, Kulkarni S, Mudipalli R, Cui B, Nishino S, Grant GA, Knowles JK, Shamloo M, Huguenard JR, Deisseroth K, Pașca SP. Maturation and circuit integration of transplanted human cortical organoids. Nature. 2022 Oct;610(7931):319-326. doi: 10.1038/s41586-022-05277-w. Epub 2022 Oct 12. PMID: 36224417; PMCID: PMC9556304.

Standard Sample Storage Conditions Have an Impact on Inferred Microbiome Composition and Antimicrobial Resistance Patterns

To culture or not to culture: careful assessment of metabarcoding data is necessary when evaluating the microbiota of a modified-atmosphere-packaged vegetarian meat alternative throughout its shelf-life period

Helix debuts online marketplace for personal genomics products - Fierce Biotech

Moopanar K, Nyide ANG, Senzani S, Mvubu NE. Clinical strains of Mycobacterium tuberculosis exhibit differential lipid metabolism-associated transcriptome changes in in vitro cholesterol and infection models. Pathog Dis. 2023 Jan 17;81:ftac046. doi: 10.1093/femspd/ftac046. PMID: 36509392; PMCID: PMC9936260.

Streamline nucleic acid extraction with BioEcho EchoLUTION™. EchoLUTION™ is a unique, one-step extraction solution that reduces time, increases productivity, and enhances downstream applications for superior results. 

Learn more about EchoLUTION™: https://hubs.ly/Q02_85qZ0

#NGS #nucleicacid #extraction #DNA #RNA

Donor-dependent fecal microbiota transplantation efficacy against necrotizing enterocolitis in preterm pigs

Ahmed, N.A., Khattab, R.A., Ragab, Y.M. et al. Safety assessment of Enterococcus lactis strains complemented with comparative genomics analysis reveals probiotic and safety characteristics of the entire species. BMC Genomics 24, 667 (2023).

The Challenges of Reconstructing Tropical Biodiversity With Sedimentary Ancient DNA: A 2200-Year-Long Metagenomic Record From Bwindi Impenetrable Forest, Uganda

Three Draft Single-Cell Genome Sequences of Novel SAR324 Strains Isolated from the Abyssopelagic Southern Ocean

Library Preparation and Sequencing Platform Introduce Bias in Metagenomic-Based Characterizations of Microbiomes

DOJ orders Admera Health to pay $5.5M to settle kickback allegations - Compliance Week

Admera Health to Explore Strategic Alternatives for Pharmacogenomics and Clinical Services Business - Business Wire

Armstrong EE, Campana MG, Solari KA, Morgan SR, Ryder OA, Naude VN, Samelius G, Sharma K, Hadly EA, Petrov DA. Genome report: chromosome-level draft assemblies of the snow leopard, African leopard, and tiger (Panthera uncia, Panthera pardus pardus, and Panthera tigris). G3 (Bethesda). 2022 Dec 1;12(12):jkac277. doi: 10.1093/g3journal/jkac277. PMID: 36250809; PMCID: PMC9713438.

We're kicking off the BVS Holiday Biotech Community Event tonight in Cambridge, MA.

Visit Sarah Deeb and Xu Zhang to discuss your next project!

Deianiraea, an extracellular bacterium associated with the ciliate Paramecium, suggests an alternative scenario for the evolution of Rickettsiales

DiVito Evans A, Fairbanks RA, Schmidt P, Levine MT. Histone methylation regulates reproductive diapause in Drosophila melanogaster. PLoS Genet. 2023 Sep 13;19(9):e1010906. doi: 10.1371/journal.pgen.1010906. PMID: 37703303; PMCID: PMC10499233.

DOJ orders Evolution Health to pay $4.5M over alleged kickbacks, false claims - Compliance Week

Genetic tests ordered by doctors race to market, while 'direct-to-consumer' tests hinge on FDA approval - STAT


  
    Parse Biosciences Welcomes Admera Health as Newest Member of Certified Service Provider Network
  

Helix Launches First Online Consumer Marketplace for DNA-Powered Products That Offer Insights on Ancestry, Entertainment, Family, Fitness, Health and Nutrition - Business Wire


  
    Admera Health Expands its Reach with Strategic Acquisition of German-based BioEcho
  

📰 Parse is excited to add Admera Health to its growing network of certified service providers!

“From the beginning, our mission at Parse Biosciences has been to make scalable single cell solutions as accessible as possible,” said Alex Rosenberg, CEO and co-founder of Parse Biosciences. “Welcoming Admera Health into our network of trusted providers furthers this mission, empowering researchers to produce high-quality single cell data for any experiment with convenience and confidence.”

Read the full release: https://parse.bio/3P6pgUi

We'll be at the BVS Holiday Biotech Community Event in Cambridge, MA tomorrow evening! Visit Admera Health's table and chat with Sarah Deeb and Xu Zhang to discuss how we can support your next project this holiday season. 

We're looking forward to seeing you there! Can't make it? Schedule a meeting with our team: https://hubs.ly/Q02-dbgg0

Unraveling Fraud Like a Double Helix: Two Whistleblowers Receive Over $860,000 for Reporting Genetic Testing Kickbacks - The National Law Review

Chinese-Based MedCDx and US-Based Admera Health Enter Into - GlobeNewswire


  
    Driving Discovery: A Look  Back at Admera Health's 2024
  

An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function

126 Corporate BoulevardSouth Plainfield, NJ 07080

Parse Biosciences

Effect of Additional Clostridium butyricum on the Intestinal Flora of Chronic Hepatitis B Patients Treated with Entecavir

Expanding Antarctic biogeography: microbial ecology of Antarctic island soils

Andersen J, Revah O, Miura Y, Thom N, Amin ND, Kelley KW, Singh M, Chen X, Thete MV, Walczak EM, Vogel H, Fan HC, Paşca SP. Generation of Functional Human 3D Cortico-Motor Assembloids. Cell. 2020 Dec 23;183(7):1913-1929.e26. doi: 10.1016/j.cell.2020.11.017. Epub 2020 Dec 16. PMID: 33333020; PMCID: PMC8711252.

We're serving up some serious savings this Thanksgiving! Harvest our latest offers: 

Spatial Transcriptomics: 10x Genomics Visium HD
Single-Cell Sequencing: 10x Genomics 3’ & 5’
Targeted Methyl-seq: EM-seq with Twist Bioscience targeted methylome panel
Partial-lane Sequencing: from $6/Gb

Inquire with a team member to get started:
https://hubs.ly/Q02Zm6dj0 

Unlock the power of spatial transcriptomics with 10x Genomics Visium HD. Explore whole transcriptome analysis from frozen, fixed frozen, and FFPE samples with continuous coverage.

Save on your next Visium HD project with our current promotion: 
https://hubs.ly/Q02_tZCD0

 #spatialbiology #spatialtranscrtipomics #NGS #VisiumHD

2024 was a year of significant growth and achievement. We're proud to have supported groundbreaking research and look forward to even greater strides in the new year. As we bid farewell to a remarkable year, let's take a moment to review our 2024 highlights! We're excited to carry this momentum into 2025🎉 

Read more about Admera Health's 2024 highlights: https://hubs.ly/Q0302rwt0

Shin J, Ding Q, Wang L, Cui Y, Baljinnyam E, Guvenek A, Tian B. CRISPRpas: programmable regulation of alternative polyadenylation by dCas9. Nucleic Acids Res. 2022 Mar 21;50(5):e25. doi: 10.1093/nar/gkab519. PMID: 34244761; PMCID: PMC8934653.

Drug company and CEO pay $47 million over alleged kickbacks and false claims - Compliance Week

DOJ and Whistleblowers Crack Down on Illegal Kickbacks: Major Qui Tam Settlements from July 2024 - JD Supra

Proper Prescribing: Pharmacogenetics Testing Gains Traction but Requires a Delicate Balancing Act - Inside Precision Medicine

Alexa M Barber and others, Whole-genome sequencing to investigate a possible genetic basis of perosomus elumbis in a calf resulting from a consanguineous mating, Translational Animal Science, Volume 5, Issue Supplement_S1, December 2021, Pages S1–S5, https://doi.org/10.1093/tas/txab171

Mac QD, Sivakumar A, Phuengkham H, Xu C, Bowen JR, Su FY, Stentz SZ, Sim H, Harris AM, Li TT, Qiu P, Kwong GA. Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors. Nat Biomed Eng. 2022 Mar;6(3):310-324. doi: 10.1038/s41551-022-00852-y. Epub 2022 Mar 3. PMID: 35241815; PMCID: PMC8957521.

Integrated DNA Technologies (IDT


  
    Admera Health Awards Grants to Seven Exceptional Researchers to Advance Their Single-Cell Studies
  

⛄Happy Holidays from Admera Health! 

We extend our sincerest greetings for a joyous holiday season and a prosperous new year! We value your trust in us and look forward to supporting your research initiatives into the new year.

Castelli M, Sabaneyeva E, Lanzoni O, Lebedeva N, Floriano AM, Gaiarsa S, Benken K, Modeo L, Bandi C, Potekhin A, Sassera D, Petroni G. Deianiraea, an extracellular bacterium associated with the ciliate Paramecium, suggests an alternative scenario for the evolution of Rickettsiales. ISME J. 2019 Sep;13(9):2280-2294. doi: 10.1038/s41396-019-0433-9. Epub 2019 May 9. PMID: 31073215; PMCID: PMC6776064.

 NuVerge announces strategic alliance with Azmera 

Genetic Testing Company to Pay $5 Million after Whistleblowers Allege Kickbacks - Whistleblower Network News


  
    Admera Health Announces its Acquisition of a NovaSeq X Plus
  

➡️Exciting news!

We're excited to announce that we're a Certified Service Provider for Parse Biosciences! Incorporating Parse's high-throughput single-cell RNA-seq into our suite of solutions, we empower researchers to scale their experiments and achieve the highest-quality results for each unique single-cell project. 

Read the full announcement: https://hubs.ly/Q030gYW50

#singlecell #NGS #scRNAseq

Happy Thanksgiving from the Admera Health team! We're thankful for your trust and partnership in advancing genomics research.

We wish you a wonderful holiday weekend!


  
    Whole Genome Sequencing at Admera Health: A Superior, End-to-End Workflow
  

Potential role of rumen bacteria in modulating milk production and composition of admixed dairy cows


  
    Admera Health Single-Cell RNA-seq Analysis
  

Tang R, Shuldiner EG, Kelly M, Murray CW, Hebert JD, Andrejka L, Tsai MK, Hughes NW, Parker MI, Cai H, Li YC, Wahl GM, Dunbrack RL, Jackson PK, Petrov DA, Winslow MM. Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth. Nat Cell Biol. 2023 Jan;25(1):159-169. doi: 10.1038/s41556-022-01049-w. Epub 2023 Jan 12. PMID: 36635501; PMCID: PMC10521195.

Parse Biosciences Welcomes Admera Health as Newest Member of Certified Service Provider Network - Business Wire

Global Pharmacogenomics Market to Surpass US$ 33,014.72 Million by 2030, Says Coherent Market Insights (CMI) - GlobeNewswire

Kemski MM, Rappleye CA, Dabrowski K, Bruno RS, Wick M. Transcriptomic response to soybean meal-based diets as the first formulated feed in juvenile yellow perch (Perca flavescens). Sci Rep. 2020 Mar 4;10(1):3998. doi: 10.1038/s41598-020-59691-z. PMID: 32132548; PMCID: PMC7055240.

Pan B, Yuan S, Mayernik L, Yap YT, Moin K, Chung CS, Maddipati K, Krawetz SA, Zhang Z, Hess RA, Chen X. Disrupted intercellular bridges and spermatogenesis in fatty acyl-CoA reductase 1 knockout mice: A new model of ether lipid deficiency. FASEB J. 2023 May;37(5):e22908. doi: 10.1096/fj.202201848R. PMID: 37039784; PMCID: PMC10150578.

A new era for discoveries at Admera Health - Illumina

Degradation profile of nixtamalized maize pericarp by the action of the microbial consortium PM-06

Shaer Tamar E, Kishony R. Multistep diversification in spatiotemporal bacterial-phage coevolution. Nat Commun. 2022 Dec 28;13(1):7971. doi: 10.1038/s41467-022-35351-w. PMID: 36577749; PMCID: PMC9797572.

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