A-Alpha Bio
Edit info- Founded: 2017
- Location: Seattle, WA
- Employee range: 11 - 50
- Funding: $22.4M A2 Jul 2023; $20M A Sep 2021; $2.8M seed Sep 2019; $225 NSF grant Jul 2018
aalphabio.com linkedin.com job board
Business:
Yeast-based Drug Assay
About:
A-Alpha Bio is accelerating drug discovery by providing cell-based tools of protein interactions. Protein interactions govern all cellular processes and are therefore linked with disease. However, while predictive tools are now available for an individual protein structure, understanding protein interactions requires time-consuming experimentation. A-Alpha is circumventing this by generating high-quality protein-protein interaction data by measuring millions of protein-protein interactions at a time using AlphaSeq. AlphaSeq combines yeast two-hybrid technology with DNA barcodes to read out high-affinity interactions. This approach can be used to discover effective antibodies and degradable neo-substrates, engineer protein interfaces, and fuel predictive machine learning models.
Jobs:
Research Associate II, Technical Operations
Seattle, WA|30 days ago
Director, Applied Data Science
Seattle, WA|100+ days ago
News:
Molecular glue deals abound - Chemical & Engineering News
googlenews
Oct 5, 2023
Funding-related
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A-Alpha Bio Collaborates with Amgen to Identify and Validate Ligase-Target Pairs for Molecular Glue Discovery - PR Web
googlenews
Sep 26, 2023
Science/business updates
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NVIDIA AI Microservices for Drug Discovery, Digital Health Now Integrated With AWS - NVIDIA Blog
googlenews
May 2, 2024
Science/business updates
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A dataset comprised of binding interactions for 104,972 antibodies against a SARS-CoV-2 peptide - Nature.com
googlenews
Oct 26, 2022
Science/business updates
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A-Alpha Bio lands $14.5M from Department of Defense to prep for future biological threats - GeekWire
googlenews
May 21, 2024
Funding-related
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High-Throughput Screening Methods to Identify Small Molecule Targets
crunchbase
Aug 31, 2022
Science/business updates
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Now hiring for a Scientist I on our Platform R&D team! Come join A-Alpha Bio on our quest to improve human health!
This person will design, execute, and analyze experiments that leverage our AlphaSeq
linkedin
May 27, 2024
New hires
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In-Silico Antibody Development with AlphaBind Using NVIDIA BioNeMo and AWS HealthOmics | NVIDIA Technical Blog
linkedin
Dec 6, 2024
Science/business updates
external-link
Now hiring for a Research Associate II on our Technical Operations team! Come join A-Alpha Bio on our quest to improve human health!
Check out the job description and application linked here - we're
linkedin
Dec 27, 2024
New hires
external-link
A-Alpha Bio wins $51M in funding to fuel ML protein research - Drug Discovery & Development
googlenews
Aug 1, 2023
Funding-related
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A-Alpha Bio and Bristol Myers Squibb to collaborate on protein degradation
crunchbase
Apr 17, 2024
Science/business updates
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A-Alpha Bio Welcomes Heidi Hagen to Its Board of Directors - PR Web
googlenews
Jun 27, 2023
New hires
external-link
We are excited to share that A-Alpha Bio has been awarded an additional $14.5M from the United States Department of Defense to enable machine learning models that rapidly predict treatments against po
linkedin
May 27, 2024
Funding-related
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Life Science Washington Institute Announces 2023 Entrepreneurial Achievement Award Winner - Business Wire
googlenews
Oct 27, 2023
Science/business updates
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Life Science Washington Institute Announces 2023 ...
crunchbase
Nov 21, 2023
Science/business updates
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A-Alpha Bio Partners with Kymera Therapeutics to Discover Novel Interactions for Molecular Glue Discovery
crunchbase
Dec 16, 2021
Science/business updates
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Protein-Protein Interactions Get a New Groove On - Genetic Engineering & Biotechnology News
googlenews
Nov 1, 2019
Science/business updates
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A-Alpha Bio Awarded Additional $14.5M from the Department of Defense to Accelerate Antibody Discovery and ...
crunchbase
May 29, 2024
Funding-related
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A-Alpha Bio, a biotech startup that measures and predicts protein interactions, raises $22.4M - GeekWire
googlenews
Jul 25, 2023
Funding-related
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A-Alpha Bio Nets $22.4M For Groundbreaking Protein Interaction Predictions
crunchbase
Aug 26, 2023
Funding-related
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UW spinout A-Alpha Bio moves off campus to Belltown tower
crunchbase
Dec 22, 2022
Science/business updates
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Now hiring for a Research Associate I on our Technical Operations team! Come join A-Alpha Bio on our quest to improve human health!
Check out the job description and application linked here - we're l
linkedin
Sep 27, 2024
New hires
external-link
A-Alpha Bio, a biotech startup that measures and predicts ...
crunchbase
Jul 25, 2023
Science/business updates
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University of Washington spinout A-Alpha Bio snags $20M for protein-discovery platform - GeekWire
googlenews
Sep 8, 2021
Funding-related
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Startup A-Alpha Bio sets out to solve a major protein problem facing big pharma
crunchbase
Sep 8, 2021
Science/business updates
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A-Alpha Bio Awarded Additional $14.5M from the Department - GlobeNewswire
googlenews
May 21, 2024
Funding-related
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Eight biotech companies thriving in Seattle
crunchbase
Feb 16, 2024
Science/business updates
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Antibody Therapeutics: Massively multiplexed affinity characterization of therapeutic antibodies against SARS-CoV-2 variants
web
Jan 2, 2025
Science/business updates
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Bud-wiser: DOD Backs A-Alpha Bio for Biothreat Preparation - Genetic Engineering & Biotechnology News
googlenews
May 21, 2024
Funding-related
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A-Alpha Bio lands $14.5M from Department of Defense to prep for future biological threats
crunchbase
May 29, 2024
Funding-related
external-link
A-Alpha Bio Raises $22.4M in Series A2 to Scale Protein-Protein Interaction Data Platforms and Accelerate Internal Pipeline Development
crunchbase
Jul 25, 2023
Funding-related
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A-Alpha Bio raises $2.8M for genetically engineered drug discovery platform - GeekWire
googlenews
Sep 24, 2019
Funding-related
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Driving Drug Discovery Success With Synthetic Biology and NGS - Technology Networks
googlenews
Jul 15, 2020
Science/business updates
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A-Alpha Bio wins $620,000 grant to work on ‘molecular glue’ for treating disease - GeekWire
googlenews
May 26, 2020
Funding-related
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Invest in your career with a Madrona-funded company. - Madrona
googlenews
Oct 29, 2018
Funding-related
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Gates Foundation awards $800K grant to A-Alpha Bio for COVID-19 treatment research - GeekWire
googlenews
Jul 9, 2020
Funding-related
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A-Alpha Bio lands $2.4M from DOD for antibody discovery project
crunchbase
May 16, 2023
Funding-related
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University of Washington spinout A-Alpha Bio snags $20M for protein-discovery platform
crunchbase
Sep 8, 2021
Funding-related
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A-Alpha Bio's David Younger on machine learning in biotech, building cross-functional teams - Madrona Venture Group
googlenews
Jan 5, 2023
Science/business updates
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40 Under 40: Randolph Lopez, A-Alpha Bio - Puget Sound Business Journal - The Business Journals
googlenews
Apr 26, 2024
New hires
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Putting the Tech in Biotech: Why Now is the Time to Build Tech-Enabled Life Science Companies - Madrona Venture Group
googlenews
Dec 14, 2022
Science/business updates
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A-Alpha Bio Nets $22.4M For Groundbreaking Protein Interaction Predictions - Yahoo Finance
googlenews
Aug 26, 2023
Funding-related
external-link
Bud-wiser: DOD Backs A-Alpha Bio for Biothreat Preparation
crunchbase
May 29, 2024
Funding-related
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Life sciences entrepreneurs offer advice on launching and building startups - GeekWire
googlenews
Oct 20, 2022
Science/business updates
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A-Alpha Bio Raises $22.4M in Series A2 to Scale Protein-Protein Interaction Data Platforms and Accelerate Internal Pipeline Development - PR Web
googlenews
Jul 25, 2023
Funding-related
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Seagen touts PhII data for Adcetris/Opdivo combo; A-Alpha partners with Gilead on HIV - Endpoints News
googlenews
Jun 13, 2023
Science/business updates
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Fenwick Represents A-Alpha Bio in $22.4 Million Series A2 Financing - Fenwick & West LLP
googlenews
Jul 25, 2023
Funding-related
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Episode 68 Changing the Game of Protein-Protein Interactions With Randolph Lopez
linkedin
Dec 13, 2024
Science/business updates
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GPR Ventures expands its property footprint in Nevada with the acquisition of Sierra View Apartments in Carson City
crunchbase
Jun 27, 2023
Science/business updates
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Check out our new AlphaBind preprint, out today on bioRxiv, demonstrating our industry-leading antibody optimization model! We are also excited to share that we have recently measured our BILLIONTH pr
linkedin
Dec 27, 2024
Science/business updates
external-link
Startup Series – Great Leaders Change Company Trajectory - Madrona Venture Group
googlenews
May 12, 2023
Science/business updates
external-link
A-Alpha Bio lands more DOD funding to expand work on biothreats
crunchbase
May 29, 2024
Funding-related
external-link
CEO Q&A: David Younger, PhD - Life Science Leader Magazine
googlenews
Jan 5, 2024
Science/business updates
external-link
A-Alpha Bio Collaborates with Amgen to Identify and Validate ...
crunchbase
Sep 26, 2023
Science/business updates
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Nature Communications: Machine learning optimization of candidate antibody yields highly diverse sub-nanomolar affinity antibody libraries
web
Jan 2, 2025
Science/business updates
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Methods for characterizing and engineering protein-protein interactions
crunchbase
Sep 2, 2022
Science/business updates
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Methods for identifying protein coding sequences using dna barcodes
crunchbase
Sep 9, 2022
Science/business updates
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