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ALX Oncology

AN2 Therapeutics

AOA Dx

ARTBIO

AS2 Bio Inc

AUM BioTech

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Abalone Bio

Abata Therapeutics

Abeona Therapeutics

Abintus Bio

Abiosciences

Absci

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Acutis Diagnostics

Adaptive Phage Therapeutics

Adcentrx Therapeutics

Adicet Bio

Adiso Therapeutics

Aditum Bio

Admera Health

Adverum Biotechnologies

Aeglea BioTherapeutics

Aera Therapeutics

Aether Bio

Affini-T Therapeutics

Affinia Therapeutics

AgBiome

Agastiya Biotech

Agena Bioscience

AiViva Biopharma

Ainnocence

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Akita Biosciences

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Alkahest

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Allarta Life Science

Allay Therapeutics

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Alzheon

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Amberstone Biosciences

Amolyt Pharma

Amylyx Pharmaceuticals

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Anagram Therapeutics

Ancora Biotech LLC

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Andson Biotech

Anebulo Pharmaceuticals

Angiex

Angiocrine Bioscience

Anima Biotech

Ankyra

Annexon Biosciences

Anodyne Nanotech

Anokion

Ansa Biotechnologies

Octant engineers human cells to understand biochemical mechanisms that link genetics to disease. Referred to as “cellular intelligence”, Octant hopes to use this information to engineer next-generation small molecule therapeutics. Genetic and clinical data collection has become easier and cheaper, but more data alone is insufficient to understand biochemical mechanisms of disease. To identify targets to drug for complex diseases, Octant is using a four-component platform: (1) high-throughput synthetic biology to engineer millions of cell lines, (2) high throughput chemistry to explore compounds that tune biochemical pathways, (3) multiplexed assays to test thousands of combinations of their engineered cells and chemicals, and (4) bioinformatics and software techniques to analyze data.

<p>Octant engineers human cells to understand biochemical mechanisms that link genetics to disease. Referred to as “cellular intelligence”, Octant hopes to use this information to engineer next-generation small molecule therapeutics.</p>
<p>Genetic and clinical data collection has become easier and cheaper, but more data alone is insufficient to understand biochemical mechanisms of disease. To identify targets to drug for complex diseases, Octant is using a four-component platform: (1) high-throughput synthetic biology to engineer millions of cell lines, (2) high throughput chemistry to explore compounds that tune biochemical pathways, (3) multiplexed assays to test thousands of combinations of their engineered cells and chemicals, and (4) bioinformatics and software techniques to analyze data.</p>


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