Senior Director, Clinical Pharmacology

Director/Senior Director, Drug Discovery Biology

1910 Genetics

20n Bio

3DBio Therapeutics

3T Biosciences

4D Molecular Therapeutics

64x Bio

76Bio

8Biomed

A-Alpha Bio

A2 Biotherapeutics

AavantiBio

Ab Studio

Abalone Bio

Abata Therapeutics

Abeona Therapeutics

Abintus Bio

Abiosciences

Absci

Accelevir Diagnostics

Accent Therapeutics

ACELYRIN

Acepodia

Achieve Life Sciences

Acrivon Therapeutics

Acutis Diagnostics

Adaptive Phage Therapeutics

Adcentrx Therapeutics

Adicet Bio

Aditum Bio

adMare BioInnovations

Admera Health

Adverum Biotechnologies

adyn

Aeglea BioTherapeutics

Aether Bio

Affini-T Therapeutics

Affinia Therapeutics

Affinivax

AgBiome

Agena Bioscience

AIRNA Bio

Akero Therapeutics

Akouos

Alamar Biosciences

Alector

AlivaMab Discovery Services

Alkahest

Alladapt Immunotherapeutics

Allakos

Allarta Life Science

Allay Therapeutics

AlloVir

Alloy Therapeutics

Alltrna

AlpaLifeBio

Alpha-9 Theranostics

Alphabioregen

Alpine Immune Sciences

Altis Biosystems

Alto Neuroscience

AltPep

Alumis

Alveo Technologies

Alveolus Bio

ALX Oncology

Alzheon

AmbAgon Therapeutics

Amberstone Biosciences

Amolyt Pharma

Amylyx Pharmaceuticals

AN2 Therapeutics

Anagram Therapeutics

Andes

Angiex

Angiocrine Bioscience

AnHeart Therapeutics

Annexon Biosciences

Anokion

Ansa Biotechnologies

Antheia

Anthos Therapeutics

AOA Dx

Apic Bio

Apollomics

Appia Bio

Applied Molecular Transport

Apriori Bio

Aptevo Therapeutics

Apton Biosystems

Aptose Biosciences

Aquinnah Pharmaceuticals

Aramis Biosciences

Arbor Biotechnologies

Arcadia Science

Arcellx

Arctoris

Arcturus Therapeutics

Arcutis Biotherapeutics

Arima Genomics

Ark Biotech

Boundless Bio is developing therapeutics directed against extrachromosomal DNA (eDNA) to treat the most intractable cancers. ecDNAs are large units of circular DNA that reside within the cell nucleus yet are distinct from the chromosomal DNA. As ecDNAs can encode genes, they provide a mechanism for higher copy numbers of oncogenes, genes that are known to drive aggressive tumor growth and resistance to cancer treatments. Boundless has identified ecDNA as a differentiating feature of cancer cells that does not exist in normal cells. By further characterizing the biology of ecDNAs using their Spyglass platform, Boundless is generating a broad pipeline of ecDNA-directed therapies (ecDTx) to target gene amplified cancers.

<p>Boundless Bio is developing therapeutics directed against extrachromosomal DNA (eDNA) to treat the most intractable cancers. ecDNAs are large units of circular DNA that reside within the cell nucleus yet are distinct from the chromosomal DNA. As ecDNAs can encode genes, they provide a mechanism for higher copy numbers of oncogenes, genes that are known to drive aggressive tumor growth and resistance to cancer treatments. Boundless has identified ecDNA as a differentiating feature of cancer cells that does not exist in normal cells. By further characterizing the biology of ecDNAs using their Spyglass platform, Boundless is generating a broad pipeline of ecDNA-directed therapies (ecDTx) to target gene amplified cancers.</p>


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