Proteovant Therapeutics is pioneering protein degradation technology for new medicines. The human body contains cellular machinery known as the ubiquitin proteome system (UPS) that targets proteins for removal. Proteovant is using this UPS machinery to create medicines that destroy disease-causing proteins. By employing protein degrader design expertise, drug development knowledge and machine learning technologies, Proteovant is identifying new ways to target the currently undruggable targets. These targets include transcription factors and scaffold proteins that lack a catalytic pocket. By using the enzymatic nature of the UPS system, efficacy is achieved at lower doses with prolonged duration, enabling Proteovant to decrease dose-limiting toxicities.

<p>Proteovant Therapeutics is pioneering protein degradation technology for new medicines. The human body contains cellular machinery known as the ubiquitin proteome system (UPS) that targets proteins for removal. Proteovant is using this UPS machinery to create medicines that destroy disease-causing proteins. By employing protein degrader design expertise, drug development knowledge and machine learning technologies, Proteovant is identifying new ways to target the currently undruggable targets. These targets include transcription factors and scaffold proteins that lack a catalytic pocket. By using the enzymatic nature of the UPS system, efficacy is achieved at lower doses with prolonged duration, enabling Proteovant to decrease dose-limiting toxicities.</p>


Proteovant Therapeutics

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